DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment cv-2 and Coch

DIOPT Version :9

Sequence 1:NP_524809.2 Gene:cv-2 / 45280 FlyBaseID:FBgn0000395 Length:751 Species:Drosophila melanogaster
Sequence 2:XP_017170432.1 Gene:Coch / 12810 MGIID:1278313 Length:555 Species:Mus musculus


Alignment Length:149 Identity:34/149 - (22%)
Similarity:53/149 - (35%) Gaps:44/149 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    31 PSTQL--LILIAVLLALLQGRTVDA-GAGDSLSGVRQSCSNEGEEVQLKNQPQIFTCFKCECQNG 92
            ||:::  |.|.|.||.||..|...| |||: |..:..:|...|.::: |.:..:.          
Mouse     2 PSSRIPALCLGAWLLLLLLPRFARAEGAGE-LVPIPVTCFTRGLDIR-KEKADVL---------- 54

  Fly    93 FVNCRDTCPPVNDCYILDKS------NGTCCRRCKGCSFRGMSYESGSEWNDPEDPCKTYKCVAT 151
                   ||  ..|.:.:.|      ..:....|.....||:...||.       |.:.|.... 
Mouse    55 -------CP--GGCSLEEFSVFGNIVYASVSSICGAAVHRGVIGTSGG-------PVRVYSLPG- 102

  Fly   152 VVTETIQKCYSQCDNNQLQ 170
                  ::.||..|.|.:|
Mouse   103 ------RENYSSVDANGIQ 115

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
cv-2NP_524809.2 VWC 184..243 CDD:214564
VWC 256..310 CDD:278520
VWC 319..376 CDD:214564
VWD 371..536 CDD:214566
C8 580..646 CDD:285899
CochXP_017170432.1 LCCL 35..117 CDD:128866 19/115 (17%)
vWA_collagen_alphaI-XII-like 169..333 CDD:238759
vWA_collagen 371..532 CDD:238749
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1216
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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