Protein Alignment cv-2 and cv-2

DIOPT Version :10

• Sequence 1: NP_524809.2
• Gene: cv-2 / 45280
• FlyBaseID: FBgn0000395
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: XP_061504823.1
• Gene: cv-2 / 1276836
• VectorBaseID: AGAMI1_002952
• Length: 737
• Species: Anopheles gambiae
• Alignment Length: 779
• Identity: 354/779 - (45%)
• Similarity: 456/779 - (58%)
• Gaps: 119/779 - (15%)

  Fly    36 LILIAVLLALLQGRTVDAGAGDSLSGVRQSCSNEGEEVQLKNQPQIFTCFKCECQNGFVNC-RDT 99
            ::|.|:::..:..|...|.|  ||||.|:.|:||||||::.     ..||||.|:||||.| :::
Mosquito    12 ILLGAIVILAISMRQATASA--SLSGYREPCTNEGEEVRIS-----MPCFKCICKNGFVECEQES 69

  Fly   100 CPPVNDCYILDKSN-GTCCRRCKGCSFRGMSYESGSEWNDPEDPCKTYKCVATVVTETIQKCYSQ 163
            ||.|:||||..|.. ..||.:|.||.::|...:||:||.||:|||..||||:.|||.:..|||:.
Mosquito    70 CPAVDDCYIYKKKGPDECCDKCIGCLYQGRHIDSGTEWTDPDDPCMHYKCVSGVVTRSEMKCYAP 134

  Fly   164 CDNNQLQPPRPGECCPTCQGCKINGQTVAEGHEVDASI-DDRCLVCQCRGTQLTCSKKTCPVLPC 227
            |.:.  .|||.|:|||||.||::|||.|..    :|:: :|.|:.|.|.|.:|||:|::||||.|
Mosquito   135 CSDP--SPPRKGQCCPTCLGCRLNGQKVLG----EATLSEDPCVKCTCSGHKLTCTKRSCPVLQC 193

  Fly   228 PMSKQIKRPDECCPRC----PQNHSFLPVPGKCLFNKSVYPEKTQFMPDRCTNCTCLNGTSVCQR 288
            |:||||:.|.||||||    .:.|...|:   |:..|:|:.....:..|:|:||||.||||||::
Mosquito   194 PLSKQIRTPGECCPRCNDRREEIHRGSPL---CILGKAVHFPGKPYHGDQCSNCTCQNGTSVCEK 255

  Fly   289 PTCPILECAPEFQ--EPDGCCPRCAV-AEVRSECSLDGIVYQNNETWDMGPCRSCRCNGGTIRCA 350
            .||||||||.|.|  ||..|||.|.: ||.||.|:..|.||||||||.:..|.||.|..|.:|||
Mosquito   256 STCPILECALEDQQREPGECCPSCPMPAEFRSTCAAAGKVYQNNETWSLNACTSCECRAGEVRCA 320

  Fly   351 QMRCPAVKCRANEELKQPPGECCQRCVETAGTCTVFGDPHFRTFDGKFFSFQGSCKYLLASDCMG 415
            .::||..||..||.|....||||.||||:...||||||||::||||.|:||||||||.|.:||:|
Mosquito   321 NIQCPKKKCGPNETLLSVSGECCPRCVESPAVCTVFGDPHYKTFDGNFYSFQGSCKYQLTADCVG 385

  Fly   416 KTFHIRLTNEGRGTRRASWAKTVTLSLRNLKVNLGQRMRVKVNGTRVTLPYFVVAGGQNVTIERL 480
            .||.||:||:.|.|:.:||.|||||.|..:|||||.|||||||||||..||.:   .|.:.|.|.
Mosquito   386 HTFSIRVTNDARLTKYSSWTKTVTLKLEGVKVNLGHRMRVKVNGTRVEPPYRL---NQTLDIHRS 447

  Fly   481 ANGGAVMLRSEMGLTLEWNGAGFLQVSVPAKFKKRLCGLCGNFNGSSRDDLTGKDG--RSHGDDE 543
            |:|..|::.:.:|:.|.|:|..|:||.||..:|.:|||||||:|...||||..:.|  .:|   .
Mosquito   448 ADGTEVIVETALGVKLSWDGLNFIQVQVPTAYKGKLCGLCGNYNSIFRDDLFTRAGLNMTH---N 509

  Fly   544 VWHFANSWKVGGPKSCS--RKREFLAATPTCDKRKSNFYCHPLSVPALFGECNERLNPENYKAAC 606
            ||.||.||.|||||:|:  ||:|..|..|.|..:|....|.||....:||.||..|||:||.|:|
Mosquito   510 VWRFARSWAVGGPKACTRQRKKELAARHPQCKTKKLYPLCKPLRTAEVFGRCNSLLNPDNYFASC 574

  Fly   607 RMDVCECPSGDCHCDSFAAYAHECRRLGVQLPDWRSATNC---------PAG---------WRRN 653
            :.|:||||...|:|||.|||||||.|.||||||||:.|.|         ||.         ...|
Mosquito   575 KFDMCECPHRQCYCDSMAAYAHECVRQGVQLPDWRTLTGCSRNASGLLPPAARAGGGPLLLLEPN 639

  Fly   654 ATLSSFKGNQFYGDPSFSR----------MKGRRQ---------------KNHQL-------RLQ 686
            |..:.....|..|..|..|          ::.|.|               |:|:|       :.|
Mosquito   640 AIDAGILQQQLPGGNSIRRHPKRLRRPKLIEQREQQGLELDLPLHLTHDRKHHKLLHHPLYRKQQ 704

  Fly   687 LQQEQQQRSKQGQKGRHKPGGHNQLDRQGHNGLDKDQLQKEFILKHVPSSFLYPRAPDRTPPPL 750
            |||:|||:.||.|         |.:..|..:|                        ..||||||
Mosquito   705 LQQQQQQQQKQQQ---------NNIPLQPISG------------------------NRRTPPPL 735

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cv-2	NP_524809.2	VWC	184..243	CDD:214564	30/59 (51%)
		VWC	256..310	CDD:278520	30/55 (55%)
		VWC	319..376	CDD:214564	29/56 (52%)
		VWD	371..536	CDD:214566	94/164 (57%)
		C8	580..646	CDD:462584	40/65 (62%)
cv-2	XP_061504823.1	None