DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cv-2 and Chrd

DIOPT Version :9

Sequence 1:	NP_524809.2	Gene:	cv-2 / 45280	FlyBaseID:	FBgn0000395	Length:	751	Species:	Drosophila melanogaster
Sequence 2:	XP_011244116.1	Gene:	Chrd / 12667	MGIID:	1313268	Length:	990	Species:	Mus musculus

Alignment Length:	248	Identity:	69/248 - (27%)
Similarity:	96/248 - (38%)	Gaps:	54/248 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   171 PPRPGECCPTCQGCKINGQTVAEGHEVDASIDDRCLVCQCRGTQLTCSKKTCPVLPCPMSKQIKR 235
            |.||.:  |..  |...||....|.....:.|..|.:|.|:...:.|....||...||  ..::.
Mouse   733 PGRPRD--PNT--CFFEGQQRPHGARWAPNYDPLCSLCICQRRTVICDPVVCPPPSCP--HPVQA 791

  Fly   236 PDECCPRCP--QNHSFLP-----VPGK-CLF--NKSVYPEKTQFMP-------DRCTNCTCLNGT 283
            .|:|||.||  |....||     .||: |.|  ::|.....|::.|       .:|..|||...|
Mouse   792 LDQCCPVCPEKQRSRDLPSLPNLEPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGAT 856

  Fly   284 SV--CQRPTCPILECA-PEFQEPDGCCPRCAV-------------AEVRSECSLDGIVYQNNETW 332
            ..  |::..||.|.|| |....|..||.:|.|             |:....|...|..:..|::|
Mouse   857 GEVHCEKVQCPRLACAQPVRANPTDCCKQCPVGSGTNAKLGDPMQADGPRGCRFAGQWFPENQSW 921

  Fly   333 --------DMGPCRSCRCNGGTIRCAQMRC-PAVKCRANEELKQPPGECCQRC 376
                    :|. |.:|||..|...|.:..| |.:.|.:.:|     ..||..|
Mouse   922 HPSVPPFGEMS-CITCRCGAGVPHCERDDCSPPLSCGSGKE-----SRCCSHC 968

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cv-2	NP_524809.2	VWC	184..243	CDD:214564	17/58 (29%)
		VWC	256..310	CDD:278520	20/65 (31%)
		VWC	319..376	CDD:214564	17/65 (26%)
		VWD	371..536	CDD:214566	3/6 (50%)
		C8	580..646	CDD:285899
Chrd	XP_011244116.1	VWC	73..147	CDD:327433
		CHRD	192..314	CDD:214804
		CHRD	322..435	CDD:214804
		CHRD	441..558	CDD:214804
		CHRD	571..683	CDD:214804
		VWC	742..799	CDD:327433	17/58 (29%)
		VWC	820..886	CDD:214564	20/65 (31%)
		VWC	908..968	CDD:327433	17/65 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910