Protein Alignment cv-2 and LOC100498375

DIOPT Version :10

• Sequence 1: NP_524809.2
• Gene: cv-2 / 45280
• FlyBaseID: FBgn0000395
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: XP_031756617.1
• Gene: LOC100498375 / 100498375
• XenbaseID: XB-GENE-29084167
• Length: 2374
• Species: Xenopus tropicalis
• Alignment Length: 715
• Identity: 173/715 - (24%)
• Similarity: 256/715 - (35%)
• Gaps: 218/715 - (30%)

  Fly    57 DSLSGVRQSCSNEGEEVQLKNQPQIFTCFKCECQNG-FVNCRDTCPPVNDCYILDKSNGTC-CRR 119
            ||:..:...||   ..|:.|.... |.|.|.:..|. |.||.....|  |.|.......|| |.|
 Frog   567 DSVELLTDPCS---LSVETKTYAD-FWCAKLKDPNSPFGNCHSAVAP--DEYYKRCEYDTCSCSR 625

  Fly   120 ------------CKGCSFRGM---SYESGSEWND-PEDPC-KTYKCVATVVTETIQK-------C 160
                        .:.|:.:|:   .:.:|:..|| |..|. :||....|....|.:.       |
 Frog   626 SDICMCAALSSYARACAAKGIILWGWRNGTCENDLPSCPASQTYLYNITTCQPTCRSLALGERDC 690

  Fly   161 YSQCDNNQLQPPRPGECCP---------------TCQGCKINGQTVAEGHEVDASIDDRCLVCQC 210
            ||:.      .|..|..||               .| .|...|..: ..:||....|:|   |.|
 Frog   691 YSEF------TPIDGCGCPDGMYLNERQKCVSLSDC-SCYFQGMYL-RPYEVIYRRDER---CSC 744

  Fly   211 RGTQLTC---SKKTCPVLPCPMSKQIKRPDECCPRCPQNHSFLPVPGKCLFNKSVYPEKTQFMPD 272
            ...:|.|   |..|||                             .||..|:.|
 Frog   745 NDGKLLCTSFSNDTCP-----------------------------NGKVFFDCS----------- 769

  Fly   273 RCTNCTCLNGTSVCQRPTCPILECAPEFQE-PDGC-CPRCAVAEVRSECSLDGI---VYQNNETW 332
                 :.|.|.::.|..:|..|...|...| ..|| ||...:.:....|..:..   .| |||.:
 Frog   770 -----SVLQGDAIPQYRSCRTLNIGPVLLECISGCVCPDGLLDDGNGGCVEERFCPCTY-NNEAY 828

  Fly   333 DMG-----PCRSCRCNGGTIRCAQMRCPAVKCRANEELKQPPGECCQRCVETAGTCTVFGDPHFR 392
            ..|     .|:||.|..|...|.|..|                         .|||.::|..|:.
 Frog   829 PHGSSLTEECKSCTCVSGIWSCIQTPC-------------------------YGTCNIYGSGHYI 868

  Fly   393 TFDGKFFSFQGSCKYLLASDCMGK---TFHIRLTNEGRGTRRASWAKTVTLSL---------RNL 445
            |||.||:.|.|||::::|.|..|.   ||.|...|...|:...:.:|::.:.|         .:|
 Frog   869 TFDKKFYDFDGSCEFVVAQDYCGDVNGTFRIITENIPCGSTGVTCSKSIKIYLGSTELKLANEHL 933

  Fly   446 KVNLGQRMRVKVNGTRVTLPYFVVAGGQNVTIERLANGGAVMLRSEMGLTLEWNGAGFLQVSVPA 510
            :..||...|.....||....|.|::...:|                   .|.|:....|.:.:.:
 Frog   934 EEILGDPARQVAYSTRELGLYLVISASNDV-------------------YLIWDRKTSLLIRLSS 979

  Fly   511 KFKKRLCGLCGNFNGSSRDD-LTGKDGRSHG--DDEVWHFANSWKVGG--------PKSC---SR 561
            .:|.:.||||||::.::.:| ||     ||.  ...|..|.||||:..        |:.|   ..
 Frog   980 SYKGKTCGLCGNYDDNANNDFLT-----SHSIQASNVMEFGNSWKLSNTCPDALELPQPCFSAPH 1039

  Fly   562 KREFLAATPTCDKRKSNFYCHPLSVPALFGECNERLNPENYKAACRMDVCECPSG---DCHCDSF 623
            :|.:  |...||...|:          :|..|:.:::|:.|..||..|||.|.:|   :|.|.:.
 Frog  1040 RRSW--AEKKCDIINSD----------VFLSCHSKVDPKPYYDACVNDVCSCDTGGDCECFCTAV 1092

  Fly   624 AAYAHECRRLGVQLPDWRSATNCPA---GWRRNATLSSFKGNQFYGDPSFSRMKGRRQKNHQLRL 685
            |||:..|.:..:.: :||:...||.   .:..|...:....:.|...|     :||  .|||:.|
 Frog  1093 AAYSQLCSKADLCI-NWRTPDICPIFCDYYNMNQKENQCMWHYFPCGP-----EGR--SNHQVTL 1149

  Fly   686  685
             Frog  1150  1149

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cv-2	NP_524809.2	VWC	184..243	CDD:214564	14/61 (23%)
		VWC	256..310	CDD:278520	13/55 (24%)
		VWC	319..376	CDD:214564	14/64 (22%)
		VWD	371..536	CDD:214566	46/177 (26%)
		C8	580..646	CDD:462584	19/68 (28%)
LOC100498375	XP_031756617.1	VWD	37..181	CDD:459671
		C8	225..292	CDD:462584
		TIL	296..352	CDD:410995
		VWD	392..546	CDD:459671
		C8	583..653	CDD:214843	17/72 (24%)
		TIL	663..720	CDD:410995	12/62 (19%)
		TIL	759..819	CDD:410995	18/104 (17%)
		VWC	821..>867	CDD:450195	17/71 (24%)
		VWD	848..1003	CDD:214566	49/203 (24%)
		C8	1043..1115	CDD:214843	23/84 (27%)
		VWD	1696..1863	CDD:214566
		C8	1905..1970	CDD:214843
		CT	2286..2368	CDD:214482