DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment csw and PTP1

DIOPT Version :9

Sequence 1:	NP_477131.1	Gene:	csw / 45278	FlyBaseID:	FBgn0000382	Length:	945	Species:	Drosophila melanogaster
Sequence 2:	NP_001031266.1	Gene:	PTP1 / 843516	AraportID:	AT1G71860	Length:	340	Species:	Arabidopsis thaliana

Alignment Length:	247	Identity:	88/247 - (35%)
Similarity:	127/247 - (51%)	Gaps:	25/247 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   521 DSS--GAVSISMAEREREREREMFKTYIATQGCLLTQQVNTVTDFWNMVWQENTRVIVMTTKEYE 583
            |||  |.|:.|:.   :..|.|....:|||||.|    .:|:.|||.||.|::..:|||.|:..:
plant   111 DSSAKGYVNASLI---KTSESESISQFIATQGPL----PHTMEDFWEMVIQQHCPIIVMLTRLVD 168

  Fly   584 RGKE-KCARYWPDEGRSEQFGHARI--QCVSENSTSDYTLREFLVSWR---DQPARRIFHYHFQV 642
            ..:. ||..|:.||....:||:..:  :.:....|| ..||...|:::   ||| ..:.|..:..
plant   169 NNRTVKCGDYFQDEDGPREFGNISLTTKWIKTTDTS-LMLRNLEVNYKETEDQP-MSVLHIQYPE 231

  Fly   643 WPDHGVPADPGCVLNFLQDVNTRQSHLAQAGEKPGPICVHCSAGIGRTGTFIVIDMILDQIVRNG 707
            |||||||.|...|...|:       .|.|.....|||.||||||||||||:..|...:.:|:...
plant   232 WPDHGVPKDTVAVREILK-------RLYQVPPSLGPIIVHCSAGIGRTGTYCAIHNTIQRILAGD 289

  Fly   708 LDTEIDIQRTIQMVRSQRSGLVQTEAQYKFVYYAVQHYIQTLIARKRAEEQS 759
            : :.:|:.:|:.:.|.||.|:|||..||.|.|.|:...::.|.|...|...|
plant   290 M-SALDLAKTVALFRKQRIGMVQTMDQYFFCYNAIVDELEDLTAGTNAGTSS 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
csw	NP_477131.1	SH2_C-SH2_SHP_like	211..307	CDD:198185
		PTPc	326..744	CDD:214550	84/230 (37%)
		PTPc	543..743	CDD:238006	76/205 (37%)
PTP1	NP_001031266.1	PTPc_plant_PTP1	117..321	CDD:350496	78/220 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102716
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900