Protein Alignment csw and ptpn9b

DIOPT Version :10

• Sequence 1: NP_477131.1
• Gene: csw / 45278
• FlyBaseID: FBgn0000382
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: XP_690659.6
• Gene: ptpn9b / 562170
• ZFINID: ZDB-GENE-090313-52
• Length: 754
• Species: Danio rerio
• Alignment Length: 813
• Identity: 176/813 - (21%)
• Similarity: 267/813 - (32%)
• Gaps: 333/813 - (40%)

  Fly    44 NNAYNNQRNFEYERAIQAHYGSKGR----------------------------RSEERERSGKFK 80
            |:.|   .||:||..::.....||.                            |.:.|||....|
Zfish   146 NSTY---ANFDYELCVKILNLLKGAFPARLKCVFIVSSPLWFRAPFAVLRLFVREKLRERVCTVK 207

  Fly    81 ASKGRKAKVTPPTETPE-----------AQEPACKNC----------MTHDELAQIIKGVAKGAD 124
            |.:  .....|.:..||           |...:|.|.          :|.|.|..::...:...|
Zfish   208 AHE--LVNHIPVSSLPEHLGGSSQYSHIAWIQSCVNSSPNHPNNSAYVTGDCLGSLLCSYSMEHD 270

  Fly   125 AQRNRDNRLQRRRRPLSAQPSAAASASTSTES-------------LHRLT--------------- 161
            ...:.|        ||:|:.|||........|             .||:|
Zfish   271 QNTSAD--------PLTAKTSAATFLGDGLNSNCPILDENNANVPNHRMTGHAHWNGSALPSLGS 327

  Fly   162 -----------PSPQASYPATPTSWTATPPQFP------AAFG----GASCSNSTLSLLATMRVQ 205
                       |.||:.          |||..|      |..|    |.:|       |...|..
Zfish   328 NANVLNGRGRQPPPQSD----------TPPDTPLHQKHTAGGGILGVGGAC-------LDASRQD 375

  Fly   206 LHGYTWFHGNLSGKEAEKLILERGKNGSFLVRESQSKPGDFVLSVRTDDKVTHVMIRWQDKKYDV 270
            .:|     ...|.::.|.|..|.|:.........:|:|.....|...|       :.|..
Zfish   376 GNG-----AEESQQDVELLEDEMGEGDGVPPLPLKSRPPPLNHSPTPD-------MSWLP----- 423

  Fly   271 GGGESFGTLSELIDHYKRNPMVETCGTVVHLRQPFNATRITAAGINARVEQLVKGGFWEEFESLQ 335
                  |.|:            ||....||:.:|..   ::...:...|::..|.|.::|:|.::
Zfish   424 ------GMLT------------ETTMLSVHVAEPGG---MSVQDLVQHVKRKKKKGIYQEYEEIR 467

  Fly   336 QD-SRDTFSRNEGYKQENRLKNRYRNILPYDHTRVKLLDV-EHSVAGAEYINANYIRLPTDGDLY 398
            :: ...||..::  |..|::||||.::|..|.:||.|..: :.....::||||:::    ||  |
Zfish   468 KEPPAGTFDYSK--KASNQIKNRYSDVLCLDQSRVHLCPLNDEDDETSDYINASFM----DG--Y 524

  Fly   399 NMSSSSESLNSSVPSCPACTAAQTQRNCSNCQLQNKTCVQCAVKSAILPYSNCATCSRKSDSLSK 463
            ..|::
Zfish   525 KWSNA------------------------------------------------------------ 529

  Fly   464 HKRSESSASSSPSSGSGSGPGSSGTSGVSSVNGPGTPTNLTSGTAGCLVGLLKRHSNDSSGAVSI 528
                                                                             
Zfish   530 ----------------------------------------------------------------- 529

  Fly   529 SMAEREREREREMFKTYIATQGCLLTQQVNTVTDFWNMVWQENTRVIVMTTKEYERGKEKCARYW 593
                            ||||||.|    ..|..|||.|||::...:|||||:..|||:.||.:||
Zfish   530 ----------------YIATQGPL----PKTFGDFWRMVWEQMVLIIVMTTRVVERGRVKCGQYW 574

  Fly   594 P-DEGRSEQFGHARIQCVSENSTSDYTLREF-LVSWRDQPARRIFHYHFQVWPDHGVPADPGCVL 656
            | :.||:|::|:..::.|......|:.|... |.:.:....|.:.||.:..|||.|||.....:|
Zfish   575 PLEAGRTEEYGYFLVRNVHIEVFQDFKLSHLELFNTQTGECREVSHYLYMSWPDFGVPKSASAML 639

  Fly   657 NFLQDVNTRQSHLAQ------AGEKPG-PICVHCSAGIGRTGTFIVIDMILDQIVRNGLDTEIDI 714
            :|...|..||....:      .|...| |:.|||||||||||||..:|:.|.::...|   .:||
Zfish   640 DFRAHVKHRQESSLRTLYPDWTGPPGGPPVVVHCSAGIGRTGTFCTLDICLSRLEDIG---TVDI 701

  Fly   715 QRTIQMVRSQRSGLVQTEAQYKFVYYAVQHYIQ 747
            ::|::.:|:||:..:||..||.|.|.||..|.|
Zfish   702 KQTVRRMRTQRAFSIQTWDQYYFCYKAVIEYGQ 734

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
csw	NP_477131.1	SH2_C-SH2_SHP_like	211..307	CDD:198185	17/95 (18%)
		PTPc-N11_6	352..748	CDD:350392	102/406 (25%)
ptpn9b	XP_690659.6	None