Protein Alignment csw and ptprz1a

DIOPT Version :10

• Sequence 1: NP_477131.1
• Gene: csw / 45278
• FlyBaseID: FBgn0000382
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: XP_005163194.2
• Gene: ptprz1a / 497461
• ZFINID: ZDB-GENE-090406-1
• Length: 1827
• Species: Danio rerio
• Alignment Length: 884
• Identity: 194/884 - (21%)
• Similarity: 297/884 - (33%)
• Gaps: 353/884 - (39%)

  Fly   112 LAQIIKGVAKGADAQRNRDNRLQRRRRPLSAQPSAAASASTSTESLH-RLTPSPQASYPATPTSW 175
            :|..:..:|:.|..|            .|.|.....:||.|.|..|. |.||:|.......|||.
Zfish   918 VAATVNNIAQSAIGQ------------SLGASAPIRSSAITPTPILELRSTPTPVVPPTIAPTSP 970

  Fly   176 T--------ATPPQFPAAFGGASCSNSTLSLLATMRVQLHGYT----WFHGNLSGKEA------- 221
            :        ..||..|.:....|.|..|.|..........|:|    |...:.||.|:
Zfish   971 SDSITVVAPVVPPTIPVSSAPESSSMPTHSADGQQENSASGWTFDLDWGQSSASGDESIAAPYIT 1035

  Fly   222 -------------------EKLILERGKNG----------------SFLVR---ESQSKPG---- 244
                               .......|:||                |:.:|   |.:|..|
Zfish  1036 TASPTEVSPEETDDGNEEHSSSFYFEGENGTESEVTDFRVTLQPSPSWTLRGSGEEESGSGETLT 1100

  Fly   245 ------DFVLSVRTDDKVTHVMIRWQDKKYDVGGG--ESFGTLSELIDHYKRN----PMVET--- 294
                  ||.:..||:.:..      ::...|....  ||...|:..|:..|:.    .:|.|
Zfish  1101 DNETSSDFSIPERTERESE------EEPVEDANNSSHESRVGLASSIERQKKAVVPLAVVSTLTF 1159

  Fly   295 ------CGTVVHLRQPF----------NATRITAAG--INAR-------VEQLVK--------GG 326
                  .|..::.|:.|          .:.|:.::.  :|..       |:|.|.        ..
Zfish  1160 LGLIFLIGIYIYWRKCFQTAHFYIEDSTSPRVISSSPLLNPTGEHEPLPVKQFVNHVTELHNTSS 1224

  Fly   327 FWEEFESLQQ--DSRDTFSRNEG------YKQENRLKNRYRNILPYDHTRVKL--LDVEHSVAGA 381
            |..|||.|::  :...|.:.:.|      ...:|:.||||.|||.|||:||:|  |:.:...:|.
Zfish  1225 FSREFEILKEYFEEVQTCTVDLGTTTDCSNHPDNKNKNRYVNILAYDHSRVRLAPLNDKDGKSGG 1289

  Fly   382 EYINANYIRLPTDGDLYNMSSSSESLNSSVPSCPACTAAQTQRNCSNCQLQNKTCVQCAVKSAIL 446
            :||||||:
Zfish  1290 DYINANYV--------------------------------------------------------- 1297

  Fly   447 PYSNCATCSRKSDSLSKHKRSESSASSSPSSGSGSGPGSSGTSGVSSVNGPGTPTNLTSGTAGCL 511
                        |..:|:
Zfish  1298 ------------DGFNKN----------------------------------------------- 1303

  Fly   512 VGLLKRHSNDSSGAVSISMAEREREREREMFKTYIATQGCLLTQQVNTVTDFWNMVWQENTRVIV 576
                                           |.|||.||.|    .::..|||.|||::|..|||
Zfish  1304 -------------------------------KAYIAAQGPL----KSSTPDFWRMVWEQNVGVIV 1333

  Fly   577 MTTKEYERGKEKCARYWPDEGRSEQFGHARIQCVSENSTSDYTLREFLV----------SWRDQP 631
            |.|...|:|::||.:|||.|.: |::|...:...|.|..:.||.|.|.:          .:|..
Zfish  1334 MITNLVEKGRKKCDQYWPLENQ-EEYGCFLVTVKSTNVLAYYTKRTFTLRNTSIKKGSQRYRSN- 1396

  Fly   632 ARRIFHYHFQVWPDHGVPADPGCVLNFLQDVNTRQSHLAQAGEKPGPICVHCSAGIGRTGTFIVI 696
            .|.:..||:..|||.|||.....||:|:...:..|:      :..||:.||||||:|||||:||:
Zfish  1397 ERTVTQYHYTQWPDMGVPEYVLPVLSFVYKSSKAQT------DGMGPMVVHCSAGVGRTGTYIVL 1455

  Fly   697 DMILDQIVRNGLDTEIDIQRTIQMVRSQRSGLVQTEAQYKFVYYA----------------VQHY 745
            |.:|.||...|   .::|...::.:|:||:.|||||.||.|.:.|                :..|
Zfish  1456 DSMLKQIKEKG---TVNIMGFLKHIRTQRNYLVQTEEQYIFTHDALVEAILSQETEVSSSHIHQY 1517

  Fly   746 IQTLI-----ARKRAEEQSLQVGREYTNIKYTGEIGNDSQRSPLPPAIS--------SISLVPSK 797
            :..|:     .:.|.|:|...|.:            ::::::....|:|        :.||:|.:
Zfish  1518 VNNLLTPGASCKTRLEKQFKLVCQ------------SNAKQNDCSAALSDCNRTKNRNCSLIPVE 1570

  Fly   798 TPLTPTSADLG-TGMGLSMGVGMGV-GNKHASKQQPPLP 834
            ......|:..| |...::....||. .||.....|.|||
Zfish  1571 KSRVCVSSSAGETSDYINASYVMGYRQNKEFIITQNPLP 1609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
csw	NP_477131.1	SH2_C-SH2_SHP_like	211..307	CDD:198185	27/175 (15%)
		PTPc-N11_6	352..748	CDD:350392	107/423 (25%)
ptprz1a	XP_005163194.2	None