Protein Alignment csw and Ptp52F

DIOPT Version :10

• Sequence 1: NP_477131.1
• Gene: csw / 45278
• FlyBaseID: FBgn0000382
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: NP_611093.2
• Gene: Ptp52F / 36790
• FlyBaseID: FBgn0034085
• Length: 1433
• Species: Drosophila melanogaster
• Alignment Length: 973
• Identity: 193/973 - (19%)
• Similarity: 309/973 - (31%)
• Gaps: 420/973 - (43%)

  Fly    18 VNHKLQEKQVYNNNNINNN----NNNTL-------NNNN------AYNNQRN----FEYERAIQA 61
            |:..:.:..|.....:|||    .|.|:       :|.:      |:|..||    ..:||.::.
  Fly   753 VSDSVTQLTVLTQGPVNNNAVYEANVTITWKVPCKSNGDIEYFQLAFNGTRNNFAPVSFERRVEL 817

  Fly    62 HYGSK-GRRS-EERERSGKFKASKGRKAKVTPPTETPEAQEPACKNCMTHDELAQIIKGVAKGAD 124
            ..|:| ||.| .|.|...:|                              |...::
  Fly   818 DTGNKQGRMSYTETEMQPQF------------------------------DYTVEV--------- 843

  Fly   125 AQRNRDNRLQRRRRPLSAQPSAAASASTSTESLHRLTPSPQASYPATPTSWTATPPQFPAAFGGA 189
            :.:|||........|.|.|..|......|.|.:.::..:.:.:...|.|:....|.....:..|
  Fly   844 SVKNRDVEQLSSSVPGSWQSPAGLPTIPSDELIKQMRANVEETSNPTKTAIVRLPADIMTSASG- 907

  Fly   190 SCSNSTLSLLATMRVQLH--GYTWFHGNLSGKEAEKL-ILERGKNGSFLVRESQSKPGDFVLSVR 251
                 .:..:|.|..|.:  |......::|....:.| ..|.|.:|:          ||..|..:
  Fly   908 -----DIKWMALMISQKNCAGVPHLKYDVSSDWPKVLSYQEAGADGT----------GDCSLEYQ 957

  Fly   252 TDDKVTHVMIRW-------QDKKYDVGGGE------SFGTLSELIDHYKRNP------------- 290
            |.::      ||       |.:..:|...|      .....||:...|...|
  Fly   958 TTEE------RWHPEPVQRQRRDGEVTSDEEIVFTIGLDKCSEVQKTYCNGPLLPDTDYNVVVRL 1016

  Fly   291 -------------------------MVETCG----------TVVHLRQPFNATRITAAGIN---- 316
                                     :|..|.          ||:.:|:.....|.:..||.
  Fly  1017 FTASGYSDAAVLNFKTKAAIKVTLILVSVCSCLLLAFVLGLTVLWVRKRLAWKRDSGQGIEDPFG 1081

  Fly   317 --------------ARVEQLVKGGFWEEFESLQQDSRD-TFSRNE-GYKQENRLKNRYRNILPYD 365
                          |:.|:|.:     ||:.:...:.: ::|.:| |..     ||||.:|.|||
  Fly  1082 NVIAKNFAIFYTEVAKPEKLAR-----EFKEITVVALELSYSASELGCH-----KNRYADIFPYD 1136

  Fly   366 HTRVKLLDVEHSVAGAEYINANYIRLPTDGDLYNMSSSSESLNSSVPSCPACTAAQTQRNCSNCQ 430
            ..|| :||::  ..|::||||::|    ||
  Fly  1137 KNRV-ILDID--AEGSDYINASFI----DG----------------------------------- 1159

  Fly   431 LQNKTCVQCAVKSAILPYSNCATCSRKSDSLSKHKRSESSASSSPSSGSGSGPGSSGTSGVSSVN 495
                                             |.|.
  Fly  1160 ---------------------------------HTRK---------------------------- 1163

  Fly   496 GPGTPTNLTSGTAGCLVGLLKRHSNDSSGAVSISMAEREREREREMFKTYIATQGCLLTQQVNTV 560
                                                           |.||||||    .:..:|
  Fly  1164 -----------------------------------------------KEYIATQG----PKPESV 1177

  Fly   561 TDFWNMVWQENTRVIVMTTKEYERGKEKCARYWPDEGRS-----------EQFGHARIQCVSENS 614
            .|||.|:.|.|.||||..|:..|....||..|:|...|.           |.:....:..|.:.
  Fly  1178 MDFWRMILQYNVRVIVQVTQFREGNTIKCHEYYPYNVRGLTVTIKSKEVLELYDRTELTVVHDK- 1241

  Fly   615 TSDYTLREFLVSWRDQPARRIFHYHFQVWPDHGVPADPGCVLNFLQDVNTRQSHLAQAGEKP--G 677
               |.|:|           ::.||:|:.|||||||.||..::.|::.|        :|.::|  .
  Fly  1242 ---YGLKE-----------KVIHYYFKKWPDHGVPEDPMHLIMFVKKV--------KAEKRPSYS 1284

  Fly   678 PICVHCSAGIGRTGTFIVIDMILDQIVRNGLDTEIDIQRTIQMVRSQRSGLVQTEAQYKFVYYAV 742
            ||.||||||:|||||||.:|:|:.::..   :::|:|..|::.:|.||..:|||:.||.|:|...
  Fly  1285 PIVVHCSAGVGRTGTFIGLDLIMQRLKS---ESKINIFETVKKLRFQRMKMVQTQQQYTFLYACT 1346

  Fly   743 QHYIQTLIARKRAEEQSLQVGREYTNIKYTGEIGNDSQRSPLPPAISSISLVPSKTPLTPTSADL 807
            ...::..|.|              ..:|..|.           |...::..:||...::....|
  Fly  1347 YELVKHKIPR--------------AALKMDGR-----------PKSVTVPAIPSPKKVSFPDVD- 1385

  Fly   808 GTGMGLSMGVGMGVGNKHASKQQPPL-------PVVNCNNNNNGIGNSGCSNGGGSSTTSSSN 863
                         ||:::.|  ..|:       |:|...:..:|:..:. ..|...:.|||||
  Fly  1386 -------------VGSEYVS--SAPITDLDDGRPIVQLPSRFSGLRRNS-PPGENDNPTSSSN 1432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
csw	NP_477131.1	SH2_C-SH2_SHP_like	211..307	CDD:198185	23/157 (15%)
		PTPc-N11_6	352..748	CDD:350392	98/408 (24%)
Ptp52F	NP_611093.2	FN3	648..749	CDD:238020
		PTPc	1100..1345	CDD:214550	104/434 (24%)