DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment csw and Ptp36E

DIOPT Version :9

Sequence 1:	NP_477131.1	Gene:	csw / 45278	FlyBaseID:	FBgn0000382	Length:	945	Species:	Drosophila melanogaster
Sequence 2:	NP_001286033.1	Gene:	Ptp36E / 35091	FlyBaseID:	FBgn0267486	Length:	682	Species:	Drosophila melanogaster

Alignment Length:	212	Identity:	68/212 - (32%)
Similarity:	103/212 - (48%)	Gaps:	21/212 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   545 YIATQGCLLTQQVNTVTDFWNMVWQENTRVIVMTTKEYERGKEKCARYWPDEGR-SEQFGHARIQ 608
            ||.|||.:    ..||..:|.||||||...|||.||.::..|..|.:|||.... .||:|...|.
  Fly   170 YIVTQGPV----EETVQAYWRMVWQENISAIVMLTKTFDFAKVMCHQYWPPNMEVHEQYGDIFIN 230

  Fly   609 CVSENSTSDYTLREFLVSWRDQ-----PARRIFHYHFQVWPDHGVPADPGCVLNFLQDVNTRQSH 668
            .|.|...:::.:|.|.:...::     ..|.|..:|:..|..|..|.. ..:|.|.:.|.....:
  Fly   231 IVREEQLANFHIRTFRLYKMNEKQEVTDERLILQFHYTEWYSHSCPFS-NALLEFRRRVRLVVGN 294

  Fly   669 LAQ-AGEKPGPICVHCSAGIGRTGTFIVIDMILDQIVRNGLDTE---IDIQRTIQMVRSQRSGLV 729
            :.: ..:..|||.||||.|.||:|.::.||..|:      |..|   .::...::.:|..|.|||
  Fly   295 IIKDEDDMRGPILVHCSDGGGRSGVYMSIDANLE------LAEEEECFNVFGYLKKLRQSRKGLV 353

  Fly   730 QTEAQYKFVYYAVQHYI 746
            :...||||:|..::.:|
  Fly   354 ENVEQYKFIYDTLEEHI 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
csw	NP_477131.1	SH2_C-SH2_SHP_like	211..307	CDD:198185
		PTPc	326..744	CDD:214550	67/208 (32%)
		PTPc	543..743	CDD:238006	67/207 (32%)
Ptp36E	NP_001286033.1	Y_phosphatase	125..368	CDD:395053	67/208 (32%)
Ptp36E	NP_001286033.1	Y_phosphatase	428..671	CDD:395053
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45443563
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840