Protein Alignment csw and Ptp10D

DIOPT Version :9

• Sequence 1: NP_477131.1
• Gene: csw / 45278
• FlyBaseID: FBgn0000382
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: NP_996413.2
• Gene: Ptp10D / 32115
• FlyBaseID: FBgn0004370
• Length: 1990
• Species: Drosophila melanogaster
• Alignment Length: 627
• Identity: 157/627 - (25%)
• Similarity: 227/627 - (36%)
• Gaps: 253/627 - (40%)

  Fly   327 FWEEFESLQQDSRD---TFSRNEGYKQENRLKNRYRNILPYDHTRVKLLDVEHSVAGAEYINANY 388
            |.||||.|:...||   ||:.    ...||.|||:.|||||||:|.||..|:.. .|::||||||
  Fly  1272 FSEEFEELKHVGRDQPCTFAD----LPCNRPKNRFTNILPYDHSRFKLQPVDDD-EGSDYINANY 1331

  Fly   389 IRLPTDGDLYNMSSSSESLNSSVPSCPACTAAQTQRNCSNCQLQNKTCVQCAVKSAILPYSNCAT 453
            :
  Fly  1332 V---------------------------------------------------------------- 1332

  Fly   454 CSRKSDSLSKHKRSESSASSSPSSGSGSGPGSSGTSGVSSVNGPGTPTNLTSGTAGCLVGLLKRH 518
                                         ||.         |.|
  Fly  1333 -----------------------------PGH---------NSP--------------------- 1338

  Fly   519 SNDSSGAVSISMAEREREREREMFKTYIATQGCLLTQQVNTVTDFWNMVWQENTRVIVMTTKEYE 583
                                    :.:|.|||.|    .:|..|||.|.|:.|:|.|||.|:.:|
  Fly  1339 ------------------------REFIVTQGPL----HSTRDDFWRMCWESNSRAIVMLTRCFE 1375

  Fly   584 RGKEKCARYWPDEGRSEQFGHARIQCVSENSTSDYTLREFLVSWRDQPARRIFHYHFQVWPDHGV 648
            :|:|||.:|||::.....:|..::|.::::..:|:.:.||::. |....|.:.|:||..|||.||
  Fly  1376 KGREKCDQYWPNDTVPVFYGDIKVQILNDSHYADWVMTEFMLC-RGSEQRILRHFHFTTWPDFGV 1439

  Fly   649 PADPGCVLNFLQDVNTRQSHLAQAGEKPGPICVHCSAGIGRTGTFIVIDMILDQIVRNGLDTEID 713
            |..|..::.|::....|      .|.:..||.||||||:||:||||.:|.||.||  |..| .:|
  Fly  1440 PNPPQTLVRFVRAFRDR------IGAEQRPIVVHCSAGVGRSGTFITLDRILQQI--NTSD-YVD 1495

  Fly   714 IQRTIQMVRSQRSGLVQTEAQYKFVYYAVQHYIQTLIARKRAEEQSLQVGRE-YTNIKYTGE--- 774
            |...:..:|.:|..:||||.||..::       |.|:|....:|..:...|| :.|..|.|:
  Fly  1496 IFGIVYAMRKERVWMVQTEQQYICIH-------QCLLAVLEGKENIVGPAREMHDNEGYEGQQVQ 1553

  Fly   775 ----------------------------------IGNDSQRSPLPPAISSISLVPSKTPLTPTSA 805
                                              |.:|.|:    |..||.:...:..|.|.:.:
  Fly  1554 LDENGDVVATIEGHLSHHDLQQAEAEAIDDENAAILHDDQQ----PLTSSFTGHHTHMPPTTSMS 1614

  Fly   806 DLGTGMGLSMGVGMGVGNKHASKQQPPL--PVVNCNNNNNGIGNSGCSNGGGSSTTSSSNGSSNG 868
            ..|.|           |..|.:...|..  .|||.::|||.:......|...|.....|.|   |
  Fly  1615 SFGGG-----------GGGHTNVDAPDRXHSVVNQSDNNNSVVIVLVDNKPSSMICKDSKG---G 1665

  Fly   869 NINALLGGIGLGLGGNMRKSNFYSDSLKQQQQREEQAPAGAG 910
            ||:.|                   :|.:||||:::|.|...|
  Fly  1666 NIDVL-------------------ESQQQQQQQQQQQPNQGG 1688

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
csw	NP_477131.1	SH2_C-SH2_SHP_like	211..307	CDD:198185
		PTPc	326..744	CDD:214550	113/419 (27%)
		PTPc	543..743	CDD:238006	76/199 (38%)
Ptp10D	NP_996413.2	fn3	124..205	CDD:278470
		fn3	220..304	CDD:278470
		fn3	315..391	CDD:278470
		FN3	405..494	CDD:238020
		FN3	511..574	CDD:238020
		FN3	583..671	CDD:238020
		fn3	683..753	CDD:278470
		fn3	787..850	CDD:278470
		fn3	866..935	CDD:278470
		fn3	961..1043	CDD:278470
		PTPc	1272..1525	CDD:214550	114/425 (27%)
		PTPc	1298..1525	CDD:238006	102/395 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45443513
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840