DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment csw and T27A3.5

DIOPT Version :9

Sequence 1:	NP_477131.1	Gene:	csw / 45278	FlyBaseID:	FBgn0000382	Length:	945	Species:	Drosophila melanogaster
Sequence 2:	NP_491761.3	Gene:	T27A3.5 / 188965	WormBaseID:	WBGene00020841	Length:	355	Species:	Caenorhabditis elegans

Alignment Length:	215	Identity:	64/215 - (29%)
Similarity:	102/215 - (47%)	Gaps:	28/215 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   545 YIATQGCLLTQQVNTVTDFWNMVWQENTRVIVMTTKEYERGKEKCARYWPDEGRSEQF---GHAR 606
            :|.|||    ....||.||:.::|||....:||.....|.||:||.:|||:....:..   |...
Worm   141 FICTQG----PTEKTVDDFYRLIWQEKAPCVVMLCNIMECGKKKCEQYWPETADGQMILMDGKLT 201

  Fly   607 IQCV--SENSTSDYTLREFLVSWRDQPARRIFHYHFQVWPDHGVPADPGCVLNFLQDVNTRQSHL 669
            ::..  ::....:..|.:..|......:....|:.::.|||.|||..|..|...|..:.|
Worm   202 VKIAEPAKEVEQNILLMKITVIDDKGTSHNFEHWQWKAWPDRGVPELPMAVFRLLIRLKT----- 261

  Fly   670 AQAGEKPGPICVHCSAGIGRTGTFIVIDMILDQIVRNGLDTEIDIQRTIQMVRSQRSGLVQTEAQ 734
                  ..||.|||||||||||:.:.:::.|   |:.....::.::..::.:|:||.|.|||:||
Worm   262 ------ASPIVVHCSAGIGRTGSIVGLEIAL---VKFCAGEKVVLKDIVKEIRNQRHGSVQTDAQ 317

  Fly   735 YKFVYYAVQHYIQTLIARKR 754
            |.|:     |.:...:|..|
Worm   318 YLFM-----HRVLLALAENR 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
csw	NP_477131.1	SH2_C-SH2_SHP_like	211..307	CDD:198185
		PTPc	326..744	CDD:214550	61/203 (30%)
		PTPc	543..743	CDD:238006	61/202 (30%)
T27A3.5	NP_491761.3	PTPc	73..326	CDD:214550	62/207 (30%)
T27A3.5	NP_491761.3	PTPc	100..326	CDD:238006	62/207 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910