DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment csw and F20H11.4

DIOPT Version :9

Sequence 1:	NP_477131.1	Gene:	csw / 45278	FlyBaseID:	FBgn0000382	Length:	945	Species:	Drosophila melanogaster
Sequence 2:	NP_498458.1	Gene:	F20H11.4 / 175937	WormBaseID:	WBGene00017647	Length:	446	Species:	Caenorhabditis elegans

Alignment Length:	264	Identity:	76/264 - (28%)
Similarity:	116/264 - (43%)	Gaps:	55/264 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   510 CLVGLLKRHS------------------------NDSSGAVSISMAEREREREREMFKTYIATQG 550
            |:...:|:||                        ||...|..::|.::.|         ||:.||
Worm   134 CVADTMKKHSEKCRYYDILCPDATRVVLQNRPPDNDFIHANWMTMPDKFR---------YISAQG 189

  Fly   551 CLLTQQVNTVTDFWNMVWQENTRVIVMTTKEYERGKEKCARYWPDEGR-SEQFGHARIQCVSENS 614
                ....||.|||:||:.|....:||.....|.|.:||:||.|.|.. |...|..||..:.:.:
Worm   190 ----PMDQTVEDFWHMVYTEKAPAVVMICDWEEDGIQKCSRYIPSEDNISHVCGIYRITKIDQMT 250

  Fly   615 T--SDYTLREFLVSWRDQ----PARRIFHYHFQVWPDHGVPADPGCVLNFLQDVNTRQSHLAQAG 673
            .  :|..|:.|.:|..|:    |:..:.||||..|.||..|.....||..|:.:        :..
Worm   251 MVYADVALQSFEISVTDKSLECPSLVVKHYHFLKWRDHTAPMTSISVLKLLKAL--------RDP 307

  Fly   674 EKPGPICVHCSAGIGRTGTFIVIDMILDQIVRNGLDTEIDIQRTIQMVRSQRSGLVQTEAQYKFV 738
            ::|||..:|||||||||.|.|.:|....:|...|   |:::...::.:|..|...||:..|:.|:
Worm   308 KRPGPPVIHCSAGIGRTATLIGVDYGNQRIGEVG---EMNVLDIVREMRQMRDKAVQSHHQFIFM 369

  Fly   739 YYAV 742
            ...:
Worm   370 LMCI 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
csw	NP_477131.1	SH2_C-SH2_SHP_like	211..307	CDD:198185
		PTPc	326..744	CDD:214550	76/264 (29%)
		PTPc	543..743	CDD:238006	67/207 (32%)
F20H11.4	NP_498458.1	Y_phosphatase	142..375	CDD:278528	74/256 (29%)
F20H11.4	NP_498458.1	PTPc	144..375	CDD:238006	72/254 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910