Protein Alignment csw and Ptpmeg2

DIOPT Version :10

• Sequence 1: NP_477131.1
• Gene: csw / 45278
• FlyBaseID: FBgn0000382
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: XP_322055.5
• Gene: Ptpmeg2 / 1282054
• VectorBaseID: AGAMI1_004321
• Length: 718
• Species: Anopheles gambiae
• Alignment Length: 663
• Identity: 153/663 - (23%)
• Similarity: 237/663 - (35%)
• Gaps: 237/663 - (35%)

  Fly   128 NRDNRLQRRRRPLSAQPSAAASASTSTESLHRLTPSPQASYPATPTSWTATPPQFPAAFGGASCS 192
            ||::.:.........||..:.|.||....:          ..|:|...:|......|..|.....
Mosquito   254 NREDEIIATAGQQQQQPQTSQSNSTDLNGV----------IGASPVMGSAGIAAIAAGTGTLDTH 308

  Fly   193 NSTLSLLATMRVQLHGYTWFHGNLS---GKEAEKLILERGKNGSFLVRESQSKPGDFVLSVRTDD 254
            :|...::.:..|.:......:..:|   |.|.|..:.....:...:|..:|..|.         :
Mosquito   309 HSLTGVVGSELVDVEFVNSHNHRVSPENGAEVEDHLNVEDISNIAVVGANQHLPA---------N 364

  Fly   255 KVTHVMIRWQDKKYDVGGGESFGTLSELIDHYKRNPMVETCGTVVHLRQPFNATR--------IT 311
            ...||            |.::..|.|||   :..||             |.:|:.        ..
Mosquito   365 HAGHV------------GHQNHHTTSEL---WTENP-------------PSSASSGFSDDDSLAG 401

  Fly   312 AAGINARVEQLV-------KGGFWEEFESLQQDSRD-TFSRNEGYKQENRLKNRYRNILPYDHTR 368
            |.|....:||:|       |.|...|:..::..:.| ||:..:  .:.|..||||.::|.|||:|
Mosquito   402 AEGDPKTIEQIVQMVRERGKMGLIREYTEIKARAPDGTFTHAK--LRNNLAKNRYTDVLCYDHSR 464

  Fly   369 VKLLDVEHSVAGAEYINANYIRLPTDGDLYNMSSSSESLNSSVPSCPACTAAQTQRNCSNCQLQN 433
            | :|..|......:|||||::    ||                         ..|:|
Mosquito   465 V-VLSQEEDDPATDYINANFV----DG-------------------------YKQKN-------- 491

  Fly   434 KTCVQCAVKSAILPYSNCATCSRKSDSLSKHKRSESSASSSPSSGSGSGPGSSGTSGVSSVNGPG 498
                                                                             
Mosquito   492 ----------------------------------------------------------------- 491

  Fly   499 TPTNLTSGTAGCLVGLLKRHSNDSSGAVSISMAEREREREREMFKTYIATQGCLLTQQVNTVTDF 563
                                                         .||:|||.|    ..|..||
Mosquito   492 ---------------------------------------------AYISTQGPL----PKTSYDF 507

  Fly   564 WNMVWQENTRVIVMTTKEYERGKEKCARYW-PDEGRSEQFGHARIQCVSENSTSDYTLREFLV-S 626
            |.|||:::..:|||||:..|||:.||.:|| |.||...::|..|::.:|..:..|||:.|..: :
Mosquito   508 WRMVWEQHCLLIVMTTRVMERGRAKCGQYWEPTEGGLAEYGSFRLRTMSIETNEDYTVVELEIRN 572

  Fly   627 WRDQPARRIFHYHFQVWPDHGVPADPGCVLNFLQDVNTRQSHLAQ------AGEKPG-PICVHCS 684
            .:....|.:.|:.|..|||:|||:....:|||||....:|:.:.:      ||...| ||.||||
Mosquito   573 IKTDEVRCVSHWQFTSWPDYGVPSSAKAMLNFLQRAREKQAEMVRALGDLWAGHPRGPPIVVHCS 637

  Fly   685 AGIGRTGTFIVIDMILDQIVRNGLDTEIDIQRTIQMVRSQRSGLVQTEAQYKFVYYAVQHYIQTL 749
            ||||||||||.:|:.:.::...|   ..||:.|::.:||||:..:|...||.|.:.|:..|
Mosquito   638 AGIGRTGTFITLDICISRLEDVG---TADIKGTVEKIRSQRAYSIQMPDQYVFCHLALIEY---- 695

  Fly   750 IARKRAEEQSLQV 762
             |..|:..||:.:
Mosquito   696 -ALSRSMLQSVDL 707

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
csw	NP_477131.1	SH2_C-SH2_SHP_like	211..307	CDD:198185	17/98 (17%)
		PTPc-N11_6	352..748	CDD:350392	106/404 (26%)
Ptpmeg2	XP_322055.5	None