DRSC/TRiP Functional Genomics Resources

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Protein Alignment csw and Ptpre

DIOPT Version :10

Sequence 1:NP_477131.1 Gene:csw / 45278 FlyBaseID:FBgn0000382 Length:945 Species:Drosophila melanogaster
Sequence 2:XP_038964618.1 Gene:Ptpre / 114767 RGDID:620771 Length:719 Species:Rattus norvegicus


Alignment Length:508 Identity:136/508 - (26%)
Similarity:188/508 - (37%) Gaps:219/508 - (43%)


- Green bases have known domain annotations that are detailed below.


  Fly   327 FWEEFESLQQDS-RDTFSRNEGYKQENRLKNRYRNILPYDHTRVKLLDVEHSVAGAEYINANYIR 390
            |.|||.||.... :.||..  ..|:|||.||||.||||.||.||.|..:: .:..::||||:|| 
  Rat   154 FREEFNSLPSGHIQGTFEL--ANKEENREKNRYPNILPNDHCRVILSQLD-GIPCSDYINASYI- 214

  Fly   391 LPTDGDLYNMSSSSESLNSSVPSCPACTAAQTQRNCSNCQLQNKTCVQCAVKSAILPYSNCATCS 455
               ||                                                            
  Rat   215 ---DG------------------------------------------------------------ 216

  Fly   456 RKSDSLSKHKRSESSASSSPSSGSGSGPGSSGTSGVSSVNGPGTPTNLTSGTAGCLVGLLKRHSN 520
                                                                             
  Rat   217 ----------------------------------------------------------------- 216

  Fly   521 DSSGAVSISMAEREREREREMFKTYIATQGCLLTQQVNTVTDFWNMVWQENTRVIVMTTKEYERG 585
                         .:|:.:     :||.||    .:..||.|||.|||::.:..|||.|...||.
  Rat   217 -------------YKEKNK-----FIAAQG----PKQETVNDFWRMVWEQRSATIVMLTNLKERK 259

  Fly   586 KEKCARYWPDEGRSEQFGHARIQCVSENST-SDYTLREFLVSWRDQP--------ARRIFHYHFQ 641
            :|||.:||||:| ...:|:.|: ||.:... .|||:|:|.:    .|        .|.:...||.
  Rat   260 EEKCYQYWPDQG-CWTYGNIRV-CVEDCVVLVDYTIRKFCI----HPQLPDSCKAPRLVSQLHFT 318

  Fly   642 VWPDHGVPADPGCVLNFLQDVNT-RQSHLAQAGEKPGPICVHCSAGIGRTGTFIVIDMILDQIVR 705
            .|||.|||..|..:|.||:.|.| ..||       .|||.||||||:||||||||||.::|.|  
  Rat   319 SWPDFGVPFTPIGMLKFLKKVKTLNPSH-------AGPIVVHCSAGVGRTGTFIVIDAMMDMI-- 374

  Fly   706 NGLDTEIDIQRTIQMVRSQRSGLVQTEAQYKFVYYAVQHY----------------IQTL----- 749
             ..:.::|:...:..:|:||..:|||:.||.|:|.|:..|                :|||     
  Rat   375 -HSEQKVDVFEFVSRIRNQRPQMVQTDVQYTFIYQALLEYYLYGDTELDVSSLERHLQTLHGTAT 438

  Fly   750 -IARKRAEEQSLQVGREYTNIKYTGE---IGNDSQRSPLPPAISS---ISLVP 795
             ..:...||:.    |:.||::...|   .||      ||..:..   |.::|
  Rat   439 HFDKIGLEEEF----RKLTNVRIMKENMRTGN------LPANMKKARVIQIIP 481

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
cswNP_477131.1 SH2_C-SH2_SHP_like 211..307 CDD:198185
PTPc-N11_6 352..748 CDD:350392 111/421 (26%)
PtpreXP_038964618.1 R-PTPc-E-1 184..412 CDD:350468 105/395 (27%)
PTP_DSP_cys 499..708 CDD:475123
Blue background indicates that the domain is not in the aligned region.

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