Protein Alignment csw and ptprr

DIOPT Version :10

• Sequence 1: NP_477131.1
• Gene: csw / 45278
• FlyBaseID: FBgn0000382
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: XP_073804489.1
• Gene: ptprr / 100526652
• ZFINID: ZDB-GENE-101029-2
• Length: 639
• Species: Danio rerio
• Alignment Length: 660
• Identity: 145/660 - (21%)
• Similarity: 206/660 - (31%)
• Gaps: 300/660 - (45%)

  Fly   122 GADAQRNRDNRLQRRRRPLSAQPSAAASASTSTESLHRLTPSPQASYPATPTSWTATPPQFPAAF 186
            ||.......|.:.:..|  :::|||....|::.      .||...|...||:|.|.:.||.|:..
Zfish   234 GAQPPLTLKNSMVQASR--TSKPSATYFPSSTN------APSCNISIHQTPSSGTTSEPQCPSGP 290

  Fly   187 GGA------SCSNSTLSLLATMRVQLHGYTWFHGNLSGKEAEKLILERGKNGSFLVRESQSKPGD 245
            ..|      ||::|...:                    |....|...||.|.|.::..|
Zfish   291 PAAELKPSVSCTHSPFRM--------------------KPVAGLQERRGSNVSLVLDMS------ 329

  Fly   246 FVLSVRTDDKVTHVMIRWQDKKYDVGGGESFGTLSELIDHYKRNPMVETCGTVV----------- 299
                                         |.|::..|           .||.|.
Zfish   330 -----------------------------SLGSVEPL-----------NCGVVTPRERATQEYLQ 354

  Fly   300 ---------HLRQPFNATRITAAGINARVEQLVKGGFWEEFESLQQ---DSRDTFSRNEGYKQEN 352
                     .||.....|.:..|                ||..:..   |.::....|.|
Zfish   355 SASRVLSRKQLRDVTQNTHVLHA----------------EFAEIPMNFVDQKELDVPNHG----- 398

  Fly   353 RLKNRYRNILPYDHTRVKLLDVEHSVAGAEYINANYIRLPTDGDLYNMSSSSESLNSSVPSCPAC 417
             .||||:.|||..|:||.|.....:...:.||||||||
Zfish   399 -SKNRYKTILPNPHSRVILKTKNSNDPLSSYINANYIR--------------------------- 435

  Fly   418 TAAQTQRNCSNCQLQNKTCVQCAVKSAILPYSNCATCSRKSDSLSKHKRSESSASSSPSSGSGSG 482
                                                                             
Zfish   436 ----------------------------------------------------------------- 435

  Fly   483 PGSSGTSGVSSVNGPGTPTNLTSGTAGCLVGLLKRHSNDSSGAVSISMAEREREREREMFKTYIA 547
                |..||.                                                  :.:||
Zfish   436 ----GYLGVE--------------------------------------------------RAFIA 446

  Fly   548 TQGCLLTQQVNTVTDFWNMVWQENTRVIVMTTKEYERGKEKCARYWPDE----GRSEQFGHARIQ 608
            |||    ..:|||.|||.|||||:..||||.||..|: .|||..|||::    |:.|
Zfish   447 TQG----PMINTVNDFWQMVWQEDCPVIVMITKLKEK-NEKCVLYWPEKRGIYGKVE-------- 498

  Fly   609 CVSENSTSD---YTLREFLVSWRDQPARRIFHYHFQVWPDHGVPADPGCVLNFLQDVNTRQSHLA 670
             ||.|:..:   |.:|...:....| :|::.||.:..||||..|...|.:|..:.||...:
Zfish   499 -VSVNNVKECDHYIIRTLNLKNGGQ-SRKVQHYWYTSWPDHKTPESAGPLLQLVNDVEEDR---- 557

  Fly   671 QAGEKPGPICVHCSAGIGRTGTFIVIDMILDQIVRNGLDTEIDIQRTIQMVRSQRSGLVQTEAQY 735
            :.....||:.|||||||||||.|:...:...|:   ||:..:|:...:..:|:.|.|::|||.||
Zfish   558 KGWTSSGPVVVHCSAGIGRTGCFMATTIGCRQL---GLEGLVDVLGIVCQLRTDRGGMIQTEEQY 619

  Fly   736 KFVYYAVQHY 745
            :||::|:..|
Zfish   620 EFVHHALSLY 629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
csw	NP_477131.1	SH2_C-SH2_SHP_like	211..307	CDD:198185	15/115 (13%)
		PTPc-N11_6	352..748	CDD:350392	101/401 (25%)
ptprr	XP_073804489.1	None