DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta5 and Psmb11

DIOPT Version :9

Sequence 1:	NP_652014.1	Gene:	Prosbeta5 / 45269	FlyBaseID:	FBgn0029134	Length:	282	Species:	Drosophila melanogaster
Sequence 2:	NP_780413.1	Gene:	Psmb11 / 73902	MGIID:	1921152	Length:	302	Species:	Mus musculus

Alignment Length:	292	Identity:	110/292 - (37%)
Similarity:	167/292 - (57%)	Gaps:	51/292 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MALAEICKISNAPYMRPNAWSSADVEEEQKGLMCNLANPYTLAAPPFENPLHNLNQIQANG---- 61
            |||.::||           |.:.|                        .|..:::..||.|
Mouse     1 MALQDVCK-----------WQTPD------------------------TPRPSIHLPQAGGWAVP 30

  Fly    62 ----DKTGVKIN---FDHGTTTLGFKFKGGVLLAVDSRATGGSYIGSQSMKKIVEINQFMLGTLA 119
                .:|.::|:   ..||||||.|:|:.||:.|.|:|::.|||:...:.:|::.::|.:|||.:
Mouse    31 RGCDPQTFLQIHGPRLAHGTTTLAFRFRHGVIAAADTRSSCGSYVACPASRKVIPVHQRLLGTTS 95

  Fly   120 GGAADCVYWDRVLSKECRLHELRNKERISVAAASKIMANIAHEYKGMGLSMGMMLAGYDKRGPGL 184
            |.:|||..|.|||.:|.||.|||..:..|||..:|::|.:...|:|:.|.:...|.|:|..||.|
Mouse    96 GTSADCATWYRVLRRELRLRELREGQLPSVAGTAKLLAAMMSCYRGLDLCVATALCGWDHSGPAL 160

  Fly   185 YYVDSEGSRTPGNLFSVGSGSLYAYGVLDSGYHWDLEDKEAQELGRRAIYHATFRDAYSGGIIRV 249
            :||.|:|:...|::|||||||.|||||||.|||:|:..:||..|.|.|:.|||.|||||||.:.:
Mouse   161 FYVYSDGTCLQGDIFSVGSGSPYAYGVLDRGYHYDMTIQEAYTLARCAVAHATHRDAYSGGSVDL 225

  Fly   250 YHIKEDGWVNISNTD-CMELHYMYQEQLKQQA 280
            :|::|.||..:|.:| |:    :|:|..|.::
Mouse   226 FHVRESGWEYVSRSDACV----LYRELQKARS 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta5	NP_652014.1	PTZ00488	38..272	CDD:185666	100/245 (41%)
Prosbeta5	NP_652014.1	proteasome_beta_type_5	74..261	CDD:239730	89/186 (48%)
Psmb11	NP_780413.1	20S_bact_beta	48..253	CDD:163402	97/208 (47%)
Psmb11	NP_780413.1	proteasome_beta_type_5	50..237	CDD:239730	89/186 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D396507at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11599
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X647
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.880