DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta5 and PSMB10

DIOPT Version :9

Sequence 1:	NP_652014.1	Gene:	Prosbeta5 / 45269	FlyBaseID:	FBgn0029134	Length:	282	Species:	Drosophila melanogaster
Sequence 2:	NP_002792.1	Gene:	PSMB10 / 5699	HGNCID:	9538	Length:	273	Species:	Homo sapiens

Alignment Length:	217	Identity:	66/217 - (30%)
Similarity:	100/217 - (46%)	Gaps:	16/217 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 FENPLHN--LNQIQANGDKTGVKINFDH----GTTTLGFKFKGGVLLAVDSRATGGSYIGSQSMK 105
            |||...|  |.::     ..|:|:  .|    |||..|..|:.||:|..|:|||..|.:..:|.:
Human    14 FENCQRNASLERV-----LPGLKV--PHARKTGTTIAGLVFQDGVILGADTRATNDSVVADKSCE 71

  Fly   106 KIVEINQFMLGTLAGGAADCVYWDRVLSKECRLHELRNKERISVAAASKIMANIAHEYKG-MGLS 169
            ||..|...:....||.|||.....|:::.:..||.|.......||..::|:......|:| :|.|
Human    72 KIHFIAPKIYCCGAGVAADAEMTTRMVASKMELHALSTGREPRVATVTRILRQTLFRYQGHVGAS 136

  Fly   170 MGMMLAGYDKRGPGLYYVDSEGSRTPGNLFSVGSGSLYAYGVLDSGYHWDLEDKEAQELGRRAIY 234
              :::.|.|..||.||.|...||.:.....::|||...|..||:..:..::..:.||.|...|:.
Human   137 --LIVGGVDLTGPQLYGVHPHGSYSRLPFTALGSGQDAALAVLEDRFQPNMTLEAAQGLLVEAVT 199

  Fly   235 HATFRDAYSGGIIRVYHIKEDG 256
            .....|..|||.:....|.:.|
Human   200 AGILGDLGSGGNVDACVITKTG 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta5	NP_652014.1	PTZ00488	38..272	CDD:185666	66/217 (30%)
Prosbeta5	NP_652014.1	proteasome_beta_type_5	74..261	CDD:239730	57/184 (31%)
PSMB10	NP_002792.1	proteasome_beta_type_7	40..227	CDD:239732	57/184 (31%)
PSMB10	NP_002792.1	Pr_beta_C	232..267	CDD:403609
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810