Protein Alignment Prosbeta5 and PSMA5

DIOPT Version :10

• Sequence 1: NP_652014.1
• Gene: Prosbeta5 / 45269
• FlyBaseID: FBgn0029134
• Length: 282
• Species: Drosophila melanogaster
• Sequence 2: NP_002781.2
• Gene: PSMA5 / 5686
• HGNCID: 9534
• Length: 241
• Species: Homo sapiens
• Alignment Length: 225
• Identity: 49/225 - (21%)
• Similarity: 99/225 - (44%)
• Gaps: 41/225 - (18%)

  Fly    73 GTTTLGFKFKGGVLLAVDSRATGGSYIGSQSMKKIVEINQFMLGTLAGGAADCVYWDRVLSKECR 137
            |:|.:|.:...||.|||:.|.| ...:...|::|||||:..:...::|..||.    :.|..:.|
Human    34 GSTAIGIQTSEGVCLAVEKRIT-SPLMEPSSIEKIVEIDAHIGCAMSGLIADA----KTLIDKAR 93

  Fly   138 L----HELRNKERISVAAASKIMANIAHEY---------KGMGLSMGMMLAGYDKRGPGLYYVDS 189
            :    |.....|.::|.:.::.::|:|.::         ......:.::..|.|::||.|:::|.
Human    94 VETQNHWFTYNETMTVESVTQAVSNLALQFGEEDADPGAMSRPFGVALLFGGVDEKGPQLFHMDP 158

  Fly   190 EGSRTPGNLFSVGSGSLYAYGVLDSGYHWDLEDKEAQELGRRAIYHATFRDAYSGGIIRVYHIKE 254
            .|:....:..::||.|..|...|...||..:                |.::|....:|.:..:.|
Human   159 SGTFVQCDARAIGSASEGAQSSLQEVYHKSM----------------TLKEAIKSSLIILKQVME 207

  Fly   255 DGWVNISNTDC------MELHYMYQEQLKQ 278
            :. :|.:|.:.      ...|...:|:|::
Human   208 EK-LNATNIELATVQPGQNFHMFTKEELEE 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta5	NP_652014.1	proteasome_beta_type_5	74..261	CDD:239730	44/199 (22%)
PSMA5	NP_002781.2	proteasome_alpha_type_5	8..220	CDD:239722	46/207 (22%)