DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta5 and Prosbeta2

DIOPT Version :9

Sequence 1:	NP_652014.1	Gene:	Prosbeta5 / 45269	FlyBaseID:	FBgn0029134	Length:	282	Species:	Drosophila melanogaster
Sequence 2:	NP_524076.2	Gene:	Prosbeta2 / 39628	FlyBaseID:	FBgn0023174	Length:	272	Species:	Drosophila melanogaster

Alignment Length:	184	Identity:	62/184 - (33%)
Similarity:	97/184 - (52%)	Gaps:	5/184 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 GTTTLGFKFKGGVLLAVDSRATGGSYIGSQSMKKI--VEINQFMLGTLAGGAADCVYWDRVLSKE 135
            |||.:|..:|.||:|..|:|||.|..:..::..||  :..|.:..|  ||.|||......::|.:
  Fly    39 GTTIVGIIYKDGVILGADTRATEGPIVSDKNCAKIHYLAKNIYCCG--AGTAADTEMTTDLISSQ 101

  Fly   136 CRLHELRNKERISVAAASKIMANIAHEYKGMGLSMGMMLAGYDKRGPGLYYVDSEGSRTPGNLFS 200
            ..||.|:....:.|.||:.::..:...|:| .:|..::|.|.||.||.:|.:...||.......:
  Fly   102 LELHRLQTDREVRVVAANTMLKQMLFRYQG-HISAALVLGGVDKTGPHIYSIHPHGSSDKLPYAT 165

  Fly   201 VGSGSLYAYGVLDSGYHWDLEDKEAQELGRRAIYHATFRDAYSGGIIRVYHIKE 254
            :|||||.|..|.:|.:..||.::|.::|.|.||....|.|..||..|.:..|::
  Fly   166 MGSGSLAAMTVFESRWKPDLSEEEGKKLVRDAIASGVFNDLGSGSNIDLCVIRK 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta5	NP_652014.1	PTZ00488	38..272	CDD:185666	62/184 (34%)
Prosbeta5	NP_652014.1	proteasome_beta_type_5	74..261	CDD:239730	61/183 (33%)
Prosbeta2	NP_524076.2	PRE1	42..232	CDD:223711	59/181 (33%)
		proteasome_beta_type_7	42..228	CDD:239732	59/181 (33%)
		Pr_beta_C	232..264	CDD:289249
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440966
Domainoid	1	1.000	44	1.000	Domainoid score	I729
eggNOG	1	0.900	-	-		E1_COG0638
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11599
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.840