DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta5 and pbs-5

DIOPT Version :9

Sequence 1:	NP_652014.1	Gene:	Prosbeta5 / 45269	FlyBaseID:	FBgn0029134	Length:	282	Species:	Drosophila melanogaster
Sequence 2:	NP_493558.1	Gene:	pbs-5 / 173334	WormBaseID:	WBGene00003951	Length:	284	Species:	Caenorhabditis elegans

Alignment Length:	222	Identity:	106/222 - (47%)
Similarity:	149/222 - (67%)	Gaps:	7/222 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 DKTGVKINFDHGTTTLGFKF-------KGGVLLAVDSRATGGSYIGSQSMKKIVEINQFMLGTLA 119
            :..|..:.|..|||||.|.:       |||:::||||||:.|.||.|:|:.||::|...|:.|:|
Worm    53 ETAGKSMQFRKGTTTLAFVYEPATPADKGGIIVAVDSRASSGEYISSKSVMKILDIGDRMVATMA 117

  Fly   120 GGAADCVYWDRVLSKECRLHELRNKERISVAAASKIMANIAHEYKGMGLSMGMMLAGYDKRGPGL 184
            ||||||.:|.|:::|.|.|:|||.|..|:|:||||..||..:.|:|.|||:|.|:|||||:||.:
Worm   118 GGAADCQFWTRIVAKYCTLYELREKTSITVSAASKYFANTLYGYRGQGLSVGSMVAGYDKKGPQI 182

  Fly   185 YYVDSEGSRTPGNLFSVGSGSLYAYGVLDSGYHWDLEDKEAQELGRRAIYHATFRDAYSGGIIRV 249
            :.|||||.|....:.|||||||.|||:||:.|...:.|.||::||.|||.|||:||:.|||:..:
Worm   183 FKVDSEGDRCQLKVCSVGSGSLNAYGILDNHYKPKMTDDEARKLGLRAIMHATYRDSGSGGVCNL 247

  Fly   250 YHIKEDGWVNISNTDCMELHYMYQEQL 276
            .||.....:.:...|..:|.|.:.::|
Worm   248 CHITPTEKIRLPPMDVSKLWYEFADEL 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta5	NP_652014.1	PTZ00488	38..272	CDD:185666	105/216 (49%)
Prosbeta5	NP_652014.1	proteasome_beta_type_5	74..261	CDD:239730	99/193 (51%)
pbs-5	NP_493558.1	Ntn_hydrolase	65..252	CDD:320988	99/186 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159080
Domainoid	1	1.000	200	1.000	Domainoid score	I1766
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55690
Inparanoid	1	1.050	210	1.000	Inparanoid score	I2376
Isobase	1	0.950	-	0	Normalized mean entropy	S454
OMA	1	1.010	-	-		QHG53702
OrthoDB	1	1.010	-	-		D396507at33208
OrthoFinder	1	1.000	-	-		FOG0001305
OrthoInspector	1	1.000	-	-		otm14414
orthoMCL	1	0.900	-	-		OOG6_100897
Panther	1	1.100	-	-	LDO	PTHR11599
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1013
SonicParanoid	1	1.000	-	-		X647
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	16	15.790