DRSC/TRiP Functional Genomics Resources

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Protein Alignment Prosbeta5 and PSMA8

DIOPT Version :9

Sequence 1:NP_652014.1 Gene:Prosbeta5 / 45269 FlyBaseID:FBgn0029134 Length:282 Species:Drosophila melanogaster
Sequence 2:NP_653263.2 Gene:PSMA8 / 143471 HGNCID:22985 Length:256 Species:Homo sapiens


Alignment Length:278 Identity:62/278 - (22%)
Similarity:115/278 - (41%) Gaps:60/278 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    36 LANPYTLAAPPFENPLHNLNQIQANGDKTGVKINFDHGTTTLGFKFKGGVLLAVDSRATGGSYIG 100
            :|:.|..|...| :|..:|.|::.  .:..||    .|:|.:|.:....|:|.|:.::. .....
Human     1 MASRYDRAITVF-SPDGHLFQVEY--AQEAVK----KGSTAVGIRGTNIVVLGVEKKSV-AKLQD 57

  Fly   101 SQSMKKIVEINQF------MLGTLAGGAADCVYWDRVLSK----ECRLHELRNKERISVAAASKI 155
            .::::||..::..      :|....|..||.    ||:..    ||:.|:|..::.::|...::.
Human    58 ERTVRKICALDDHVCMAFAVLTIFIGLTADA----RVVINRARVECQSHKLTVEDPVTVEYITRF 118

  Fly   156 MANIAHEY------KGMGLSMGMMLAGYDKRG-PGLYYVDSEGSRTPGNLFSVGSGSLYAYGVLD 213
            :|.:..:|      :..|:|  .::.|:|..| ..||..|..|:.......::|..:......|:
Human   119 IATLKQKYTQSNGRRPFGIS--ALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLE 181

  Fly   214 SGYHWD--LEDKEAQELGRRAIYHATFRDAYSGG------IIR------VYHIKEDGWVNISNTD 264
            ..|..|  ..|.||.:|..:|:...    ..|||      |||      ::..||          
Human   182 KNYTEDAIASDSEAIKLAIKALLEV----VQSGGKNIELAIIRRNQPLKMFSAKE---------- 232

  Fly   265 CMELHYMYQEQLKQQAAK 282
             :||:....|:.|::|.|
Human   233 -VELYVTEIEKEKEEAEK 249

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Prosbeta5NP_652014.1 PTZ00488 38..272 CDD:185666 57/264 (22%)
proteasome_beta_type_5 74..261 CDD:239730 46/217 (21%)
PSMA8NP_653263.2 PRK03996 5..237 CDD:235192 57/260 (22%)
proteasome_alpha_type_7 5..219 CDD:239724 50/231 (22%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0638
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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