DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cathD and AT4G04460

DIOPT Version :9

Sequence 1:	NP_001334713.1	Gene:	cathD / 45268	FlyBaseID:	FBgn0029093	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_192355.1	Gene:	AT4G04460 / 825776	AraportID:	AT4G04460	Length:	508	Species:	Arabidopsis thaliana

Alignment Length:	436	Identity:	181/436 - (41%)
Similarity:	234/436 - (53%)	Gaps:	114/436 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 PLSNYMDAQYYGPIAIGSPPQNFRVVFDTGSSNLWVPSKKCHLTNIACLMHNKYDASKSKTYTKN 128
            ||.||:||||||.|.||:|||.|.|:|||||||||:||.||:| ::||..|:||.||:|.:|.||
plant    78 PLKNYLDAQYYGDITIGTPPQKFTVIFDTGSSNLWIPSTKCYL-SVACYFHSKYKASQSSSYRKN 141

  Fly   129 GTEFAIQYGSGSLSGYLSTDTVSIAGLDIKDQTFAEALSEPGLVFVAAKFDGILGLGYNSISVDK 193
            |...:|:||:|::|||.|.|.|.:..:.:|:|.|.||.||||:.|:.||||||||||:..|||..
plant   142 GKPASIRYGTGAISGYFSNDDVKVGDIVVKEQEFIEATSEPGITFLLAKFDGILGLGFKEISVGN 206

  Fly   194 VKPPFYAMYEQGLISAPVFSFYLNRDPASPEGGEIIFGGSDPNHYTGEFTYLPVTRKAYWQIKMD 258
            ..|.:|.|.|:||:..|:|||:|||:|..||||||:|||.||.|:.||.|::|||.|.|||..|
plant   207 STPVWYNMVEKGLVKEPIFSFWLNRNPKDPEGGEIVFGGVDPKHFKGEHTFVPVTHKGYWQFDM- 270

  Fly   259 AASIGDLQL-------CKGGCQVIADTGTSLIAAPLEEATSINQKIGGTPII------------- 303
                ||||:       |..||..|||:||||:..|....|.||..||...|:
plant   271 ----GDLQIAGKPTGYCAKGCSAIADSGTSLLTGPSTVITMINHAIGAQGIVSRECKAVVDQYGK 331

  Fly   304 --------------------------------GGQYVVS-------------------------- 310
                                            |.|.||.
plant   332 TMLNSLLAQEDPKKVCSQIGVCAYDGTQSVSMGIQSVVDDGTSGLLNQAMCSACEMAAVWMESEL 396

  Fly   311 ----------------CDLIP--------------QLPVIKFVLGGKTFELEGKDYILRVAQMGK 345
                            ||.||              .:|::.|.:||::|:|..:|||.::.:..:
plant   397 TQNQTQERILAYAAELCDHIPTQNQQSAVDCGRVSSMPIVTFSIGGRSFDLTPQDYIFKIGEGVE 461

  Fly   346 TICLSGFMGLDIPPPNGPLWILGDVFIGKYYTEFDMGNDRVGFADA 391
            :.|.|||..:||.||.||||||||:|:|.|:|.||.|..|||||.|
plant   462 SQCTSGFTAMDIAPPRGPLWILGDIFMGPYHTVFDYGKGRVGFAKA 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cathD	NP_001334713.1	None
AT4G04460	NP_192355.1	phytepsin	77..506	CDD:133162	179/433 (41%)
		SapB_2	321..353	CDD:367521	0/31 (0%)
		SapB_1	380..417	CDD:368325	2/36 (6%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	368	1.000	Domainoid score	I182
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	383	1.000	Inparanoid score	I524
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	1	1.000	-	-		mtm978
orthoMCL	1	0.900	-	-		OOG6_100536
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X163
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840