Protein Alignment cathD and bace1

DIOPT Version :9

• Sequence 1: NP_001334713.1
• Gene: cathD / 45268
• FlyBaseID: FBgn0029093
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: NP_001072485.1
• Gene: bace1 / 779940
• XenbaseID: XB-GENE-5787150
• Length: 502
• Species: Xenopus tropicalis
• Alignment Length: 404
• Identity: 103/404 - (25%)
• Similarity: 164/404 - (40%)
• Gaps: 94/404 - (23%)

  Fly    43 ADVGTEL--------QQLRIRYGGGDVPEPLSNYMDAQYYGPIAIGSPPQNFRVVFDTGSSNLWV 99
            |:.|.||        ..||.:.|.|             ||..:.:|:|||...::.||||||..|
 Frog    51 AEKGMELDTNFLDMIDNLRGKSGQG-------------YYVEMRVGTPPQTLNILVDTGSSNFAV 102

  Fly   100 -----PSKKCHLTNIACLMHNKYDASKSKTYTKNGTEFAIQYGSGSLSGYLSTDTVSIA-GLDIK 158
                 |..|.:           |....|:||........:.|..|...|.|.||.|:|. |.::.
 Frog   103 GAAPHPFLKRY-----------YHRQHSRTYRDVRRGVYVPYTQGKWEGELGTDLVTIPHGPNVT 156

  Fly   159 DQTFAEALSEPGLVFV-AAKFDGILGLGYNSIS--VDKVKPPFYAMYEQGLISAPVFS------- 213
            ......|:::....|: .:.::|||||.|..|:  .|.::|.|.::.:|..: ..:||
 Frog   157 VTANIAAITDSDKFFINGSNWEGILGLAYAEIARPDDTLEPFFDSLVKQTRV-PNIFSLQLCGTG 220

  Fly   214 FYLNR-DPASPEGGEIIFGGSDPNHYTGEFTYLPVTRKAYWQIKMDAASIG--DLQL-CK--GGC 272
            |:.|. |.::..||.::.||.||:.|.|...|.|:.::.|:::.:....|.  ||.: ||  ...
 Frog   221 FHFNESDTSASVGGSMVIGGIDPSLYIGSIWYTPIRKEWYYEVIIVKIEINGQDLHMDCKEYNYD 285

  Fly   273 QVIADTGTSLIAAPLE---------EATSINQKIGGTPIIGGQYVVSC---DLIPQ--LPVIKFV 323
            :.|.|:||:.:..|..         :|.|..:|......:|.|.|  |   ...|.  .|||...
 Frog   286 KSIVDSGTTNLRLPKRVFDAAVKSIKAASSTEKFPDGFWLGEQLV--CWQEGTTPWHIFPVISLY 348

  Fly   324 LGG----KTFELE--GKDYILRVAQMG-------KTICLSGFMGLDIPPPNGPLWILGDVFIGKY 375
            |.|    ::|::.  .:.|:..|..:.       |........|.          ::|.|.:..:
 Frog   349 LMGEVANQSFKITILPQQYLRPVEDIATAQEDCYKFAVSQSTTGT----------VMGAVIMEGF 403

  Fly   376 YTEFDMGNDRVGFA 389
            |..||..|.|:|||
 Frog   404 YVVFDRANKRIGFA 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cathD	NP_001334713.1	None
bace1	NP_001072485.1	beta_secretase_like	73..438	CDD:133140	97/382 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910