Protein Alignment cathD and Napsa

DIOPT Version :9

• Sequence 1: NP_001334713.1
• Gene: cathD / 45268
• FlyBaseID: FBgn0029093
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: NP_113858.1
• Gene: Napsa / 60575
• RGDID: 61940
• Length: 420
• Species: Rattus norvegicus
• Alignment Length: 396
• Identity: 194/396 - (48%)
• Similarity: 255/396 - (64%)
• Gaps: 12/396 - (3%)

  Fly     6 LLLVAFLAAAVAHPNSQEKPGLLRVPLHKFQSARRHFADV-GTELQQLRIR---YGGGDVPEPLS 66
            |||   |...|...|.:....|:||||.:.....|.|:.: |.|.:....|   .||.....|||
  Rat     6 LLL---LLCLVLLGNLEPAATLIRVPLRRIHPGHRIFSPLYGWEQRAELSRTPTSGGKTAFVPLS 67

  Fly    67 NYMDAQYYGPIAIGSPPQNFRVVFDTGSSNLWVPSKKCHLTNIACLMHNKYDASKSKTYTKNGTE 131
            .:|:.||:|.|.:|:|||||.||||||||||||||.:||..::||..|::::...|.::..|||:
  Rat    68 KFMNTQYFGDIGLGTPPQNFTVVFDTGSSNLWVPSTRCHFFSLACWFHHRFNPKASSSFRPNGTK 132

  Fly   132 FAIQYGSGSLSGYLSTDTVSIAGLDIKDQTFAEALSEPGLVFVAAKFDGILGLGYNSISVDKVKP 196
            ||||||:|.|||.||.|.::|.|:.....||.|||.||.|||..|:||||||||:.:::|..|:|
  Rat   133 FAIQYGTGRLSGILSRDNLTIGGIHNVSVTFGEALWEPSLVFALARFDGILGLGFPTLAVGGVQP 197

  Fly   197 PFYAMYEQGLISAPVFSFYLNRDPASPEGGEIIFGGSDPNHYTGEFTYLPVTRKAYWQIKMDAAS 261
            |..|:.||.|:..||||||||||....:|||::.|||||:||....|::|||..||||:.|.:..
  Rat   198 PLDALVEQRLLEKPVFSFYLNRDSEGSDGGELVLGGSDPDHYVPPLTFIPVTIPAYWQVHMQSVK 262

  Fly   262 IG-DLQLCKGGCQVIADTGTSLIAAPLEEATSINQKIGGTPIIGGQYVVSCDLIPQLPVIKFVLG 325
            :| .|.||..||..|.|||||||..|.||..::|:.:||.|::.|||::.|..||:||.:.|.||
  Rat   263 VGTGLNLCAQGCGAILDTGTSLITGPSEEIRALNKAVGGFPLLTGQYLIQCSKIPELPTVSFSLG 327

  Fly   326 GKTFELEGKDYILRVAQMGKTICLSGFMGLDIPPPNGPLWILGDVFIGKYYTEFDMGN----DRV 386
            |..|.|.|:||::::.|....:||.||..||||.|.||||||||||:|.|...||.|:    .||
  Rat   328 GVWFNLTGQDYVIKILQSDVGLCLLGFQALDIPKPEGPLWILGDVFLGSYVAVFDRGDKNIGPRV 392

  Fly   387 GFADAK 392
            |.|.|:
  Rat   393 GLARAR 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cathD	NP_001334713.1	None
Napsa	NP_113858.1	pepsin_retropepsin_like	69..395	CDD:299705	171/325 (53%)
		Asp	73..397	CDD:278455	171/323 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100536
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X163
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.790