Protein Alignment cathD and pgc.2

DIOPT Version :10

• Sequence 1: NP_652013.1
• Gene: cathD / 45268
• FlyBaseID: FBgn0029093
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: NP_001025603.1
• Gene: pgc.2 / 594991
• XenbaseID: XB-GENE-964422
• Length: 385
• Species: Xenopus tropicalis
• Alignment Length: 401
• Identity: 156/401 - (38%)
• Similarity: 228/401 - (56%)
• Gaps: 36/401 - (8%)

  Fly     7 LLVAFLAAAVAHPNSQEKPGLLRVPLHKFQSARRHFADVG-------TELQQLRIRYG---GGDV 61
            :::||:...::.       ||:||||||.::.|....:.|       |..::..::|.   ..|.
 Frog     4 VILAFVCLQISE-------GLIRVPLHKSKTIRETMKEKGVLKEFMKTHKREPAMKYKYNLKNDF 61

  Fly    62 P---EPLSNYMDAQYYGPIAIGSPPQNFRVVFDTGSSNLWVPSKKCHLTNIACLMHNKYDASKSK 123
            .   ||:  ||||.|||.|::|:|||||.|:||||||||||.|..|.  :.||..|..::.|:|.
 Frog    62 AIAYEPM--YMDAAYYGQISVGTPPQNFMVLFDTGSSNLWVASTYCQ--SGACQNHPLFNPSQSS 122

  Fly   124 TYTKNGTEFAIQYGSGSLSGYLSTDTVSIAGLDIKDQTFAEALSEPGLVFVAAKFDGILGLGYNS 188
            |||....:|:|.||||||:|....|||::.||.|.:|....:::|||..||.:.|:||.|:.|.:
 Frog   123 TYTSKNQQFSITYGSGSLTGVFGYDTVTVQGLSITNQEIGLSINEPGTNFVYSSFEGIFGMAYPA 187

  Fly   189 ISVDKVKPPFYAMYEQGLISAPVFSFYLNRDPASPEGGEIIFGGSDPNHYTGEFTYLPVTRKAYW 253
            ::......|...|.:|.|::.|:||.|:     |.:.||:||||.|.:.|:|:..:.|||::.||
 Frog   188 LAAGGATTPMQGMLQQNLLTYPIFSVYM-----SSQSGEVIFGGVDSSLYSGQIYWAPVTQELYW 247

  Fly   254 QIKMDAASIGDLQL--CKGGCQVIADTGTSLIAAPLEEATSINQKIGGTPIIGGQYVVSCDLIPQ 316
            ||.:|..||.....  |..|||.:.||||||:..|.:...:..|.:|......|:|:|:|:.:..
 Frog   248 QIAIDEFSINGQATGWCSQGCQAMVDTGTSLLTVPQQFMGTFLQSLGAQQNQYGEYIVNCNNVQS 312

  Fly   317 LPVIKFVLGGKTFELEGKDYILRVAQMGKTICLSGFMGLDIPPPNG-PLWILGDVFIGKYYTEFD 380
            ||.|.|.:.|..|.:....|||:    ....|..|.....:|..|| |.|||||||:.:||:.:|
 Frog   313 LPPISFTINGVQFPIPPSAYILQ----NNGYCSVGVEVTYLPSQNGQPFWILGDVFLRQYYSVYD 373

  Fly   381 MGNDRVGFADA 391
            |||:|||||.:
 Frog   374 MGNNRVGFAQS 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cathD	NP_652013.1	A1_Propeptide	29..56	CDD:462326	9/33 (27%)
		pepsin_retropepsin_like	62..389	CDD:472175	139/332 (42%)
pgc.2	NP_001025603.1	A1_Propeptide	19..45	CDD:462326	8/25 (32%)
		pepsin_retropepsin_like	71..382	CDD:472175	135/321 (42%)