Protein Alignment cathD and Bace2

DIOPT Version :9

• Sequence 1: NP_001334713.1
• Gene: cathD / 45268
• FlyBaseID: FBgn0029093
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: NP_062390.3
• Gene: Bace2 / 56175
• MGIID: 1860440
• Length: 514
• Species: Mus musculus
• Alignment Length: 378
• Identity: 90/378 - (23%)
• Similarity: 150/378 - (39%)
• Gaps: 101/378 - (26%)

  Fly    73 YYGPIAIGSPPQNFRVVFDTGSSNLWVPSKKCHLTNIACLMHNKYDASKSKTYTKNGTEFAIQYG 137
            ||..:.||:|||..:::.||||||..|.... |     ..:...:|:..|.||...|.:..::|.
Mouse    88 YYLEMLIGTPPQKVQILVDTGSSNFAVAGAP-H-----SYIDTYFDSESSSTYHSKGFDVTVKYT 146

  Fly   138 SGSLSGYLSTDTVSIAG-------LDIKDQTFAEALSEPGLVFVAAKFDGILGLGYNSISVDKVK 195
            .||.:|::..|.|:|..       ::|.....:|....||:     |::|||||.|.:::    |
Mouse   147 QGSWTGFVGEDLVTIPKGFNSSFLVNIATIFESENFFLPGI-----KWNGILGLAYAALA----K 202

  Fly   196 PP------FYAMYEQGLISAPVFSFY-----LNRDPASPEGGEIIFGGSDPNHYTGEFTYLPVTR 249
            |.      |.::..|..| ..:||..     |....:...||.::.||.:|:.|.|:..|.|:..
Mouse   203 PSSSLETFFDSLVAQAKI-PDIFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIWYTPIKE 266

  Fly   250 KAYWQIKMDAASIGDLQL---CK--GGCQVIADTGTSLIAAPLEEATSINQKIGGTPII------ 303
            :.|:||::....||...|   |:  ...:.|.|:||:|:..|.:...::.:.:..|.:|
Mouse   267 EWYYQIEILKLEIGGQNLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVARTSLIPEFSDG 331

  Fly   304 ---GGQYVVSC-----------------------------DLIPQLPVIKFVLGGKTFELEGKDY 336
               |.|  ::|                             .::|||.:...:..|..:|
Mouse   332 FWTGAQ--LACWTNSETPWAYFPKISIYLRDENASRSFRITILPQLYIQPMMGAGFNYE------ 388

  Fly   337 ILRVAQMGKTICLSGFMGLDIPPPNGPLWILGDVFIGKYYTEFDMGNDRVGFA 389
            ..|......|..|                ::|...:..:|..||....|||||
Mouse   389 CYRFGISSSTNAL----------------VIGATVMEGFYVVFDRAQRRVGFA 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cathD	NP_001334713.1	None
Bace2	NP_062390.3	beta_secretase_like	85..446	CDD:133140	90/378 (24%)
		Asp	88..425	CDD:278455	88/376 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810