Protein Alignment cathD and pgc

DIOPT Version :10

• Sequence 1: NP_652013.1
• Gene: cathD / 45268
• FlyBaseID: FBgn0029093
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: NP_001015682.1
• Gene: pgc / 548353
• XenbaseID: XB-GENE-5838607
• Length: 385
• Species: Xenopus tropicalis
• Alignment Length: 380
• Identity: 154/380 - (40%)
• Similarity: 221/380 - (58%)
• Gaps: 29/380 - (7%)

  Fly    26 GLLRVPLHKFQSARRHFADVG-------TELQQLRIRYGG------GDVPEPLSNYMDAQYYGPI 77
            ||:||||.:|:|.|....:.|       |..::..|:|..      |...||:  |:|..|:|.|
 Frog    16 GLVRVPLKRFKSTRETMKENGVLNDFLKTHKREPAIKYNWNSQSNFGVAYEPM--YLDIYYFGEI 78

  Fly    78 AIGSPPQNFRVVFDTGSSNLWVPSKKCHLTNIACLMHNKYDASKSKTYTKNGTEFAIQYGSGSLS 142
            :||:|||||.|.||||||||||.|..|.  :.||..|..::.|.|.|||.|..:|::.|||||::
 Frog    79 SIGTPPQNFLVAFDTGSSNLWVASTYCQ--SQACTNHPLFNPSLSSTYTSNNQQFSMWYGSGSMT 141

  Fly   143 GYLSTDTVSIAGLDIKDQTFAEALSEPGLVFVAAKFDGILGLGYNSISVDKVKPPFYAMYEQGLI 207
            |.|..|||::.||.|::|....:::||...|..:|||||.|:.|.|:|..........:.:|.||
 Frog   142 GVLGYDTVTVQGLSIQNQELGLSVTEPSSFFYYSKFDGIFGMAYQSLSAGGASTAVQGLIQQNLI 206

  Fly   208 SAPVFSFYLNRDPASPEGGEIIFGGSDPNHYTGEFTYLPVTRKAYWQIKMDAASIGDLQL--CKG 270
            ..|||||||     :.:.||:||||.|.:.::|:..:.|||::.||||.:|..|:.....  |..
 Frog   207 PQPVFSFYL-----TSQSGEVIFGGVDNSLFSGQIYWTPVTQEIYWQIAIDEFSVNGQATGWCSQ 266

  Fly   271 GCQVIADTGTSLIAAPLEEATSINQKIGGTPIIGGQYVVSCDLIPQLPVIKFVLGGKTFELEGKD 335
            |||.|.||||.|:..|.:..:::.|.:|......||::|:|:.:..||.|.|.:.|..|.:....
 Frog   267 GCQGIVDTGTPLLTIPQQYLSTLVQYVGAQEAQNGQFLVNCNSVQNLPPISFTISGIQFSIPPSA 331

  Fly   336 YILRVAQMGKTICLSGFMGLDIPPPNG-PLWILGDVFIGKYYTEFDMGNDRVGFA 389
            |||::    ...|:.||....:|..|| |||||||||:.:||:.:|.||::||||
 Frog   332 YILQM----NGYCVVGFESTYLPSRNGQPLWILGDVFLRQYYSVYDFGNNQVGFA 382

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cathD	NP_652013.1	A1_Propeptide	29..56	CDD:462326	10/33 (30%)
		pepsin_retropepsin_like	62..389	CDD:472175	138/329 (42%)
pgc	NP_001015682.1	A1_Propeptide	19..45	CDD:462326	8/25 (32%)
		pepsin_retropepsin_like	71..383	CDD:472175	137/323 (42%)