Protein Alignment cathD and ren

DIOPT Version :10

• Sequence 1: NP_652013.1
• Gene: cathD / 45268
• FlyBaseID: FBgn0029093
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: NP_998025.1
• Gene: ren / 405786
• ZFINID: ZDB-GENE-040630-3
• Length: 395
• Species: Danio rerio
• Alignment Length: 395
• Identity: 172/395 - (43%)
• Similarity: 238/395 - (60%)
• Gaps: 18/395 - (4%)

  Fly     7 LLVAFLAAAVAHPNSQEKPGLLRVPLHKFQSARRHFADVGTE----LQQLRIRY-----GGGDVP 62
            ||:..|:|.       ....|.||.|.|..|.|....::...    |.::..:|     ..|..|
Zfish     8 LLILSLSAI-------STKALWRVKLKKMPSIRETLKEMSVTPAQVLSEIMPKYQEPSPTNGTAP 65

  Fly    63 EPLSNYMDAQYYGPIAIGSPPQNFRVVFDTGSSNLWVPSKKCHLTNIACLMHNKYDASKSKTYTK 127
            .||.||:|.||:|.|:||||.|.|.|||||||:||||||..|.....||..||:||||||.|:..
Zfish    66 TPLINYLDTQYFGEISIGSPAQMFNVVFDTGSANLWVPSHSCSPLYTACFTHNRYDASKSLTHIF 130

  Fly   128 NGTEFAIQYGSGSLSGYLSTDTVSIAGLDIKDQTFAEALSEPGLVFVAAKFDGILGLGYNSISVD 192
            |||.|:|||.||::.|:||.|.|.:.|:.:. |.||||.:.|.:.|:.|||||:||:||.::::|
Zfish   131 NGTGFSIQYASGNVRGFLSEDVVVVGGIPVV-QVFAEATALPAIPFILAKFDGVLGMGYPNVAID 194

  Fly   193 KVKPPFYAMYEQGLISAPVFSFYLNRDPASPEGGEIIFGGSDPNHYTGEFTYLPVTRKAYWQIKM 257
            .:.|.|..:..|.::...|||.|.:|||....|||::.||:|||::||.|.|:....:..|::.|
Zfish   195 GITPVFDRIMSQHVLKENVFSVYYSRDPTHIPGGELVLGGTDPNYHTGPFHYINTKEQGKWEVIM 259

  Fly   258 DAASIG-DLQLCKGGCQVIADTGTSLIAAPLEEATSINQKIGGTPIIGGQYVVSCDLIPQLPVIK 321
            ...|:| |:..||.||..:.|||:|.|..|....:.:.:.||...:..|.|.|||:::..||.:.
Zfish   260 KGVSVGADILFCKDGCTAVIDTGSSYITGPASSISILMKTIGAVELAEGGYTVSCNVVRLLPTVA 324

  Fly   322 FVLGGKTFELEGKDYILRVAQMGKTICLSGFMGLDIPPPNGPLWILGDVFIGKYYTEFDMGNDRV 386
            |.|||:.:.|..:||||..::.|:.||...|..||:|||.||:||||..||.:||||||.||:|:
Zfish   325 FHLGGQEYSLTDEDYILWQSEFGEDICTVTFKALDVPPPTGPVWILGANFIARYYTEFDRGNNRI 389

  Fly   387 GFADA 391
            |||.|
Zfish   390 GFARA 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cathD	NP_652013.1	A1_Propeptide	29..56	CDD:462326	7/30 (23%)
		pepsin_retropepsin_like	62..389	CDD:472175	155/327 (47%)
ren	NP_998025.1	A1_Propeptide	23..>38	CDD:462326	6/14 (43%)
		renin_like	68..394	CDD:133154	155/326 (48%)