Protein Alignment cathD and Bace

DIOPT Version :9

• Sequence 1: NP_001334713.1
• Gene: cathD / 45268
• FlyBaseID: FBgn0029093
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: NP_001285756.1
• Gene: Bace / 34182
• FlyBaseID: FBgn0032049
• Length: 372
• Species: Drosophila melanogaster
• Alignment Length: 393
• Identity: 187/393 - (47%)
• Similarity: 244/393 - (62%)
• Gaps: 40/393 - (10%)

  Fly     6 LLLVAFLAAAVAHPNSQEKPGLLRVPLHKFQSARRHFADVGTELQQLRIRYGGGDVP-------E 63
            ::|:|.||:|..|          |||:.|.|:..:...:|..|...||.:|   .:|       |
  Fly     8 VVLLAALASAELH----------RVPILKEQNFVKTRQNVLAEKSYLRTKY---QLPSLRSVDEE 59

  Fly    64 PLSNYMDAQYYGPIAIGSPPQNFRVVFDTGSSNLWVPSKKCHLTNIACLMHNKYDASKSKTYTKN 128
            .|||.|:..|||.|:||:|.|:|:|:||:|||||||||..|  .:.|||.||:||:|.|.||..|
  Fly    60 QLSNSMNMAYYGAISIGTPAQSFKVLFDSGSSNLWVPSNTC--KSDACLTHNQYDSSASSTYVAN 122

  Fly   129 GTEFAIQYGSGSLSGYLSTDTVSIAGLDIKDQTFAEALSEPGLVFVAAKFDGILGLGYNSISVDK 193
            |..|:||||:|||:||||||||.:.||.|:.|||||:.:|||..|..|.||||||:.|.|::||.
  Fly   123 GESFSIQYGTGSLTGYLSTDTVDVNGLSIQSQTFAESTNEPGTNFNDANFDGILGMAYESLAVDG 187

  Fly   194 VKPPFYAMYEQGLISAPVFSFYLNRDPASPEGGEIIFGGSDPNHYTGEFTYLPVTRKAYWQIKMD 258
            |.||||.|..|||:...||||||.||..|..|||:||||||.:.|:|..||:|::.:.|||..|.
  Fly   188 VAPPFYNMVSQGLVDNSVFSFYLARDGTSTMGGELIFGGSDASLYSGALTYVPISEQGYWQFTMA 252

  Fly   259 AASIGDLQLCKGGCQVIADTGTSLIAAPLEEATSINQKIGGTPIIGGQYVVSCDLIPQLPVIKFV 323
            .:||....|| ..||.|||||||||.||.....::::.:.    :|....:.|..:..||.:.|.
  Fly   253 GSSIDGYSLC-DDCQAIADTGTSLIVAPYNAYITLSEILN----VGEDGYLDCSSVSSLPDVTFN 312

  Fly   324 LGGKTFELEGKDYILRVAQMGKTICLSGF--MGLDIPPPNGPLWILGDVFIGKYYTEFDMGNDRV 386
            :||..|.|:...||::    ....|:|.|  ||.|       .|||||||||:||||||:||:|:
  Fly   313 IGGTNFVLKPSAYIIQ----SDGNCMSAFEYMGTD-------FWILGDVFIGQYYTEFDLGNNRI 366

  Fly   387 GFA 389
            |||
  Fly   367 GFA 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cathD	NP_001334713.1	None
Bace	NP_001285756.1	pepsin_retropepsin_like	59..369	CDD:299705	168/327 (51%)
		Asp	68..371	CDD:278455	165/320 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455561
Domainoid	1	1.000	97	1.000	Domainoid score	I1884
eggNOG	1	0.900	-	-		E1_KOG1339
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I1684
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	1	1.000	-	-		mtm978
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.900