Protein Alignment cathD and Bace2

DIOPT Version :9

• Sequence 1: NP_001334713.1
• Gene: cathD / 45268
• FlyBaseID: FBgn0029093
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: NP_001002802.1
• Gene: Bace2 / 288227
• RGDID: 1303241
• Length: 514
• Species: Rattus norvegicus
• Alignment Length: 378
• Identity: 92/378 - (24%)
• Similarity: 150/378 - (39%)
• Gaps: 101/378 - (26%)

  Fly    73 YYGPIAIGSPPQNFRVVFDTGSSNLWVPSKKCHLTNIACLMHNKYDASKSKTYTKNGTEFAIQYG 137
            ||..:.||:|||..|::.||||||..|.... |     ..:...:|:..|.||...|.|..::|.
  Rat    88 YYLEMLIGTPPQKVRILVDTGSSNFAVAGAP-H-----SYIDTYFDSESSSTYHSKGFEVTVKYT 146

  Fly   138 SGSLSGYLSTDTVSIAG-------LDIKDQTFAEALSEPGLVFVAAKFDGILGLGYNSISVDKVK 195
            .||.:|::..|.|:|..       ::|.....:|....||:     |::|||||.|.:::    |
  Rat   147 QGSWTGFVGEDLVTIPKGFNSSFLVNIATIFESENFFLPGI-----KWNGILGLAYAALA----K 202

  Fly   196 PP------FYAMYEQGLISAPVFSFY-----LNRDPASPEGGEIIFGGSDPNHYTGEFTYLPVTR 249
            |.      |.::..|..| ..:||..     |....:...||.::.||.:|:.|.|:..|.|:..
  Rat   203 PSSSLETFFDSLVAQAKI-PDIFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIWYTPIKE 266

  Fly   250 KAYWQIKMDAASIGDLQL---CK--GGCQVIADTGTSLIAAPLEEATSINQKIGGTPII------ 303
            :.|:||::....||...|   |:  ...:.|.|:||:|:..|.:...::.:.:..|.:|
  Rat   267 EWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVARTSLIPEFSDG 331

  Fly   304 ---GGQYVVSC-----------------------------DLIPQLPVIKFVLGGKTFELEGKDY 336
               |.|  ::|                             .::|||.:...:..|..:|
  Rat   332 FWTGAQ--LACWTNSETPWAYFPKISIYLRDENASRSFRITILPQLYIQPMMGAGFNYE------ 388

  Fly   337 ILRVAQMGKTICLSGFMGLDIPPPNGPLWILGDVFIGKYYTEFDMGNDRVGFA 389
            ..|......|..|                ::|...:..:|..||....|||||
  Rat   389 CYRFGISSSTNAL----------------VIGATVMEGFYVVFDRAQRRVGFA 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cathD	NP_001334713.1	None
Bace2	NP_001002802.1	beta_secretase_like	85..446	CDD:133140	92/378 (24%)
		Asp	88..425	CDD:278455	90/376 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810