Protein Alignment cathD and yps1

DIOPT Version :10

• Sequence 1: NP_652013.1
• Gene: cathD / 45268
• FlyBaseID: FBgn0029093
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: NP_588035.1
• Gene: yps1 / 2538927
• PomBaseID: SPCC1795.09
• Length: 521
• Species: Schizosaccharomyces pombe
• Alignment Length: 410
• Identity: 86/410 - (20%)
• Similarity: 152/410 - (37%)
• Gaps: 93/410 - (22%)

  Fly    42 FADVGTELQQLRIRYGGGDV---PEPLSNYMDAQYYGPIAIGSPPQNFRVVFDTGSSNLWVPSKK 103
            |.:...:|::....|....:   |..|.:|  ..|...::||.|..::.|..|......|:....
pombe    35 FPNQENQLEKRDYTYSPSGITSFPLDLQSY--TYYTTTLSIGRPSISYTVAIDLDMPYTWLTYYN 97

  Fly   104 ---------------------------CHLTNIACLMHNKYDASKSKTYTKNGTEFAIQYGSGSL 141
                                       |...:.:|...|   ||.|..:..:.:.|.|:|
pombe    98 VMAFNPAYLGIVNSGTQWSTDELRYFLCKKESDSCYFGN---ASSSFHFVTSPSTFFIRY----- 154

  Fly   142 SGYLSTDTVSIAGLDIKDQ-TFAEALSEPGLVF-VAAK---------FDGILGLG----YNSI-- 189
                 .|.:::||::::|. :::...:.|...| :..|         :.|:|||.    .|||
pombe   155 -----DDNITVAGINVQDSLSYSHYQALPDFQFGITLKEYVPSSMLPYKGVLGLAASTEINSIDY 214

  Fly   190 --SVDKVKPPFY--AMYEQGLISAPVFSFYLNRDPASPEGGEIIFGGSDPNHYTGEFTYLPVTRK 250
              |:....||.:  .:.::.:::.|.||.||:    :...|.::.|..|.:.|.|:|..|..|:.
pombe   215 SDSISSFSPPTFLEQLVKEDILAYPAFSMYLD----NQGNGSLLLGAVDTSKYQGQFVALKQTKL 275

  Fly   251 AYWQIKMDAASIGDLQLCK----GGCQVIAD----TGTSLIAAPLEEATSINQKIGGTPIIGGQY 307
            .::     |.||..:|...    ....:|.|    |..:.|..|.|.|.|:... .|..:..|.:
pombe   276 THY-----AVSIYSVQFLNSTFFSNYSIITDAYFQTRETYIYLPAELAYSVMDN-AGAYLSEGYF 334

  Fly   308 VVSCDLIPQLPVIKFVLG-GKTFELEGKDYILRVAQMGKTICLSGFMGLDIPPPNGPLWILGDVF 371
            .::||.|.....:.|..| ..|.::...  :|.:.|: ..|||.|     |.|......:||.:|
pombe   335 ALNCDEIDLEAALIFQFGCNSTIKVPIS--LLVIGQV-SNICLLG-----IRPSTDSEIVLGLLF 391

  Fly   372 IGKYYTEFDMGNDRVGFADA 391
            ....||.:......:....|
pombe   392 FRNAYTFYHQSQKMIAIGQA 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cathD	NP_652013.1	A1_Propeptide	29..56	CDD:462326	2/13 (15%)
		pepsin_retropepsin_like	62..389	CDD:472175	82/383 (21%)
yps1	NP_588035.1	pepsin_retropepsin_like	66..411	CDD:472175	79/375 (21%)