DRSC/TRiP Functional Genomics Resources

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Protein Alignment cathD and Ren

DIOPT Version :10

Sequence 1:NP_652013.1 Gene:cathD / 45268 FlyBaseID:FBgn0029093 Length:392 Species:Drosophila melanogaster
Sequence 2:NP_036774.4 Gene:Ren / 24715 RGDID:3554 Length:402 Species:Rattus norvegicus


Alignment Length:396 Identity:168/396 - (42%)
Similarity:235/396 - (59%) Gaps:14/396 - (3%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 LLVAFLAAAVAHPNSQEKPGLLRVPLHKFQSARRHFADVGTELQQLRIRYGG-------GDVPEP 64
            ||:.:.:.:.:.|......|  |:.|.|..|.|....:.|.::.::...:|.       .:|..|
  Rat    11 LLLLWTSCSFSLPTDTASFG--RILLKKMPSVREILEERGVDMTRISAEWGEFIKKSSFTNVTSP 73

  Fly    65 --LSNYMDAQYYGPIAIGSPPQNFRVVFDTGSSNLWVPSKKCHLTNIACLMHNKYDASKSKTYTK 127
              |:||:|.||||.|.||:|.|.|:|:|||||:||||||.||.....||.:||.||:|:|.:|.:
  Rat    74 VVLTNYLDTQYYGEIGIGTPSQTFKVIFDTGSANLWVPSTKCGPLYTACEIHNLYDSSESSSYME 138

  Fly   128 NGTEFAIQYGSGSLSGYLSTDTVSIAGLDIKDQTFAEALSEPGLVFVAAKFDGILGLGYNSISVD 192
            |||||.|.||||.:.|:||.|.|::.|: |..|||.|....|.:.|:.|||||:||:|:.:.:||
  Rat   139 NGTEFTIHYGSGKVKGFLSQDVVTVGGI-IVTQTFGEVTELPLIPFMLAKFDGVLGMGFPAQAVD 202

  Fly   193 KVKPPFYAMYEQGLISAPVFSFYLNRDPASPEGGEIIFGGSDPNHYTGEFTYLPVTRKAYWQIKM 257
            .|.|.|..:..|.::...|||.|.:|: :...|||::.|||||.||.|.|.|:.:::...|||.|
  Rat   203 GVIPVFDHILSQRVLKEEVFSVYYSRE-SHLLGGEVVLGGSDPQHYQGNFHYVSISKAGSWQITM 266

  Fly   258 DAASIGDLQ-LCKGGCQVIADTGTSLIAAPLEEATSINQKIGGTPIIGGQYVVSCDLIPQLPVIK 321
            ...|:|... ||:.||..:.|||||.|:.|......|.|.:|........|||:|..:|.||.|.
  Rat   267 KGVSVGPATLLCEEGCMAVVDTGTSYISGPTSSLQLIMQALGVKEKRANNYVVNCSQVPTLPDIS 331

  Fly   322 FVLGGKTFELEGKDYILRVAQMGKTICLSGFMGLDIPPPNGPLWILGDVFIGKYYTEFDMGNDRV 386
            |.|||:|:.|...||:.:.......:|:....|||||||.||:|:||..||.|:|||||..|:|:
  Rat   332 FYLGGRTYTLSNMDYVQKNPFRNDDLCILALQGLDIPPPTGPVWVLGATFIRKFYTEFDRHNNRI 396

  Fly   387 GFADAK 392
            |||.|:
  Rat   397 GFALAR 402

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
cathDNP_652013.1 A1_Propeptide 29..56 CDD:462326 6/26 (23%)
pepsin_retropepsin_like 62..389 CDD:472175 153/329 (47%)
RenNP_036774.4 A1_Propeptide 31..64 CDD:462326 7/32 (22%)
renin_like 76..401 CDD:133154 154/326 (47%)

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