Protein Alignment cathD and Cym

DIOPT Version :10

• Sequence 1: NP_652013.1
• Gene: cathD / 45268
• FlyBaseID: FBgn0029093
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: NP_001104613.1
• Gene: Cym / 229697
• MGIID: 2684977
• Length: 379
• Species: Mus musculus
• Alignment Length: 402
• Identity: 143/402 - (35%)
• Similarity: 217/402 - (53%)
• Gaps: 35/402 - (8%)

  Fly     1 MQKVALLLVAFLAAAVAHPNSQEKPGLLRVPLHKFQSARRHFADVGT----------ELQQLRIR 55
            |::..|||.| ||.:.:|.       :.|:||||.:|.|....:.|.          |..:...|
Mouse     1 MRRFVLLLAA-LAISQSHV-------VTRIPLHKGKSLRNTLKEQGLLEDFLSRQQYEFSEKNSR 57

  Fly    56 YGGGDVPEPLSNYMDAQYYGPIAIGSPPQNFRVVFDTGSSNLWVPSKKCHLTNIACLMHNKYDAS 120
            . |....|||.||:|::|:|.|.||:|||.|.||||||||.|||||..|:  :..|..|:::|.|
Mouse    58 I-GVVASEPLINYLDSEYFGTIYIGTPPQEFTVVFDTGSSELWVPSVYCN--SKVCRNHHRFDPS 119

  Fly   121 KSKTYTKNGTEFAIQYGSGSLSGYLSTDTVSIAGLDIKDQTFAEALSEPGLVFVAAKFDGILGLG 185
            ||.|:........:|||:|.:.|:|:.|||:::.:.:..||...:..|||.:|..:.|||||||.
Mouse   120 KSITFQNLSKPLFVQYGTGRMEGFLAYDTVTVSDIVVSHQTVGLSTQEPGDIFTYSPFDGILGLA 184

  Fly   186 YNSISVDKVKPPFYAMYEQGLISAPVFSFYLNRDPASPEGGEIIFGGSDPNHYTGEFTYLPVTRK 250
            |.:.:.....|.|..|..:.|::..:||.|::|   :.:|..:..|..|.:::.|...::|||.:
Mouse   185 YPTFASKYSVPIFDNMMNRHLVAQDLFSVYMSR---NEQGSMLTLGAIDQSYFIGSLHWVPVTVQ 246

  Fly   251 AYWQIKMDAASI-GDLQLCKGGCQVIADTGTSLIAAPLEEATSINQKIGGTPIIGGQYVVSCDLI 314
            .|||..:|..:| |::..|:|||..:.||||:|:..|..:..:|.|.||.......|:.:.|..:
Mouse   247 GYWQFTVDRITINGEVVACQGGCPAVLDTGTALLTGPGRDILNIQQVIGAVQGHNDQFDIDCWRL 311

  Fly   315 PQLPVIKFVLGGKTFELEGKDYILRVAQMGKTICLSGFMGLDIPPPNGPLWILGDVFIGKYYTEF 379
            ..:|.:.|.:.|:.|.|....|..:|    :..|.|||      .....:||||||||.::|:.|
Mouse   312 DIMPTVVFEIHGREFPLPPYAYTNQV----QGFCSSGF------KQGSHMWILGDVFIREFYSVF 366

  Fly   380 DMGNDRVGFADA 391
            |..|:|||.|.|
Mouse   367 DRANNRVGLAKA 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cathD	NP_652013.1	A1_Propeptide	29..56	CDD:462326	9/36 (25%)
		pepsin_retropepsin_like	62..389	CDD:472175	122/327 (37%)
Cym	NP_001104613.1	A1_Propeptide	21..47	CDD:462326	8/25 (32%)
		pepsin_retropepsin_like	64..377	CDD:472175	122/327 (37%)