Protein Alignment cathD and Ren1

DIOPT Version :9

• Sequence 1: NP_001334713.1
• Gene: cathD / 45268
• FlyBaseID: FBgn0029093
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: NP_112469.1
• Gene: Ren1 / 19701
• MGIID: 97898
• Length: 402
• Species: Mus musculus
• Alignment Length: 374
• Identity: 160/374 - (42%)
• Similarity: 227/374 - (60%)
• Gaps: 12/374 - (3%)

  Fly    29 RVPLHKFQSARRHFADVGTELQQLRIRYG---------GGDVPEPLSNYMDAQYYGPIAIGSPPQ 84
            |:||.|..|.|....:.|.::.:|...:|         ....|..|:||::.||||.|.||:|||
Mouse    31 RIPLKKMPSVREILEERGVDMTRLSAEWGVFTKRPSLTNLTSPVVLTNYLNTQYYGEIGIGTPPQ 95

  Fly    85 NFRVVFDTGSSNLWVPSKKCHLTNIACLMHNKYDASKSKTYTKNGTEFAIQYGSGSLSGYLSTDT 149
            .|:|:|||||:||||||.||....:||.:|:.|::|.|.:|.:||::|.|.||||.:.|:||.|:
Mouse    96 TFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGSDFTIHYGSGRVKGFLSQDS 160

  Fly   150 VSIAGLDIKDQTFAEALSEPGLVFVAAKFDGILGLGYNSISVDKVKPPFYAMYEQGLISAPVFSF 214
            |::.|:.: .|||.|....|.:.|:.|||||:||:|:.:.:|..|.|.|..:..||::...|||.
Mouse   161 VTVGGITV-TQTFGEVTELPLIPFMLAKFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSV 224

  Fly   215 YLNRDPASPEGGEIIFGGSDPNHYTGEFTYLPVTRKAYWQIKMDAASIG-DLQLCKGGCQVIADT 278
            |.||. :...|||::.|||||.||.|.|.|:.:::...|||.|...|:| ...||:.||.|:.||
Mouse   225 YYNRG-SHLLGGEVVLGGSDPQHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDT 288

  Fly   279 GTSLIAAPLEEATSINQKIGGTPIIGGQYVVSCDLIPQLPVIKFVLGGKTFELEGKDYILRVAQM 343
            |:|.|:||......|.|.:|.......:|||:|..:|.||.|.|.|||:.:.|...||:|:....
Mouse   289 GSSFISAPTSSLKLIMQALGAKEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNR 353

  Fly   344 GKTICLSGFMGLDIPPPNGPLWILGDVFIGKYYTEFDMGNDRVGFADAK 392
            ...:|......:|||||.||:|:||..||.|:|||||..|:|:|||.|:
Mouse   354 RDKLCTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cathD	NP_001334713.1	None
Ren1	NP_112469.1	A1_Propeptide	29..54	CDD:285240	7/22 (32%)
		renin_like	76..401	CDD:133154	149/326 (46%)
		Asp	83..401	CDD:278455	146/319 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X163
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	8	7.880