Protein Alignment cathD and asp-4

DIOPT Version :9

• Sequence 1: NP_001334713.1
• Gene: cathD / 45268
• FlyBaseID: FBgn0029093
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: NP_510191.1
• Gene: asp-4 / 181444
• WormBaseID: WBGene00000217
• Length: 444
• Species: Caenorhabditis elegans
• Alignment Length: 410
• Identity: 204/410 - (49%)
• Similarity: 270/410 - (65%)
• Gaps: 22/410 - (5%)

  Fly     4 VALLLVAFLAAAVAHPNSQEKPGLLRVPLHKFQSARRHFADVGTELQQLRIRYG----------- 57
            :.|||.|.|.....|.:.:::. |..|.|.|..:.|......|:.....:.|:|
 Worm     5 ILLLLGALLLVQGLHVHKRQQK-LRTVSLKKQPTLRETLLQAGSFETFAKHRHGYKKYLKTNGNH 68

  Fly    58 ----------GGDVPEPLSNYMDAQYYGPIAIGSPPQNFRVVFDTGSSNLWVPSKKCHLTNIACL 112
                      .|::.|.|.|||||||:|.|:||:|.|||.|:|||||||||:|||||...:|||:
 Worm    69 HFDKYQALNVEGEIDELLRNYMDAQYFGTISIGTPAQNFTVIFDTGSSNLWIPSKKCPFYDIACM 133

  Fly   113 MHNKYDASKSKTYTKNGTEFAIQYGSGSLSGYLSTDTVSIAGLDIKDQTFAEALSEPGLVFVAAK 177
            :|::||:..|.||.::|.:.|||||:||:.|::|.|:|.:||:..:||.||||.||||:.|||||
 Worm   134 LHHRYDSKSSSTYKEDGRKMAIQYGTGSMKGFISKDSVCVAGVCAEDQPFAEATSEPGITFVAAK 198

  Fly   178 FDGILGLGYNSISVDKVKPPFYAMYEQGLISAPVFSFYLNRDPASPEGGEIIFGGSDPNHYTGEF 242
            ||||||:.|..|:|..|:|.|..::||..:.:.:|||:|||:|.|..||||.|||.|...|....
 Worm   199 FDGILGMAYPEIAVLGVQPVFNTLFEQKKVPSNLFSFWLNRNPDSEIGGEITFGGIDSRRYVEPI 263

  Fly   243 TYLPVTRKAYWQIKMDAASIGDLQLCKGGCQVIADTGTSLIAAPLEEATSINQKIGGTPIIGGQY 307
            ||:|||||.|||.|||......:..|..|||.||||||||||.|..:..:|...||..|:|.|:|
 Worm   264 TYVPVTRKGYWQFKMDKVVGSGVLGCSNGCQAIADTGTSLIAGPKAQIEAIQNFIGAEPLIKGEY 328

  Fly   308 VVSCDLIPQLPVIKFVLGGKTFELEGKDYILRVAQMGKTICLSGFMGLDIPPPNGPLWILGDVFI 372
            ::|||.:|.||.:.||:||:.|.|:|:||:|:|:|.|||||||||||:|:|...|.|||||||||
 Worm   329 MISCDKVPTLPPVSFVIGGQEFSLKGEDYVLKVSQGGKTICLSGFMGIDLPERVGELWILGDVFI 393

  Fly   373 GKYYTEFDMGNDRVGFADAK 392
            |:||:.||...:|||||.||
 Worm   394 GRYYSVFDFDQNRVGFAQAK 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cathD	NP_001334713.1	None
asp-4	NP_510191.1	pepsin_retropepsin_like	88..411	CDD:386101	184/322 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159213
Domainoid	1	1.000	388	1.000	Domainoid score	I414
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55616
Inparanoid	1	1.050	408	1.000	Inparanoid score	I1060
Isobase	1	0.950	-	0	Normalized mean entropy	S917
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	1	1.000	-	-		otm14085
orthoMCL	1	0.900	-	-		OOG6_100536
Panther	1	1.100	-	-	LDO	PTHR47966
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3883
SonicParanoid	1	1.000	-	-		X163
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	17	16.750