Protein Alignment cathD and asp-3

DIOPT Version :9

• Sequence 1: NP_001334713.1
• Gene: cathD / 45268
• FlyBaseID: FBgn0029093
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: NP_509142.2
• Gene: asp-3 / 180947
• WormBaseID: WBGene00000216
• Length: 398
• Species: Caenorhabditis elegans
• Alignment Length: 400
• Identity: 184/400 - (46%)
• Similarity: 245/400 - (61%)
• Gaps: 25/400 - (6%)

  Fly     7 LLVAFLAAAVAHPNSQEKPGLLRVPLHKFQSARRHFADVGTELQQLRIRYGGGDVP------EPL 65
            ||:|.:|.|.|         :.|:.|.|....|..: ..|:..:.|:.:|..|.:|      |.|
 Worm     7 LLLALVALASA---------IQRIKLEKRTYTREQY-KFGSIQEHLKAKYVPGYIPNKDAFNEGL 61

  Fly    66 SNYMDAQYYGPIAIGSPPQNFRVVFDTGSSNLWVPSKKCHLTNIACLMHNKYDASKSKTYTKNGT 130
            |:|.:||||||:.||:|||||:|:|||||||||||...|...:|||.|||::|..||.:.|..|.
 Worm    62 SDYSNAQYYGPVTIGTPPQNFQVLFDTGSSNLWVPCANCPFGDIACRMHNRFDCKKSSSCTATGA 126

  Fly   131 EFAIQYGSGSLSGYLSTDTVSIAGLDI-----KDQTFAEALSEPGLVFVAAKFDGILGLGYNSIS 190
            .|.||||:||:.|.:..|.|.. |.|.     |:|..|.|.||||:.|||||||||.|:|:::||
 Worm   127 SFEIQYGTGSMKGTVDNDVVCF-GHDTTYCTDKNQGLACATSEPGITFVAAKFDGIFGMGWDTIS 190

  Fly   191 VDKVKPPFYAMYEQGLI-SAPVFSFYLNRDPAS-PEGGEIIFGGSDPNHYTGEFTYLPVTRKAYW 253
            |:|:..|...::....| ...:|:|:|:||... ..||||....:|||||.|...:.|:..:.||
 Worm   191 VNKISQPMDQIFANSAICKNQLFAFWLSRDANDITNGGEITLCDTDPNHYVGNIAWEPLVSEDYW 255

  Fly   254 QIKMDAASIGDLQLCKGGCQVIADTGTSLIAAPLEEATSINQKIGGTPIIGGQYVVSCDLIPQLP 318
            :||:.:..|.......|....|.||||||:..|.:....|..||||.|:..|:|.|.|..||.||
 Worm   256 RIKLASVVIDGTTYTSGPIDSIVDTGTSLLTGPTDVIKKIQHKIGGIPLFNGEYEVECSKIPSLP 320

  Fly   319 VIKFVLGGKTFELEGKDYILRVAQ-MGKTICLSGFMGLDIPPPNGPLWILGDVFIGKYYTEFDMG 382
            .|.|.|||:.|:|:||||||:::. .|.:.|||||||:|||.|.||||||||||||::|:.||.|
 Worm   321 NITFNLGGQNFDLQGKDYILQMSNGNGGSTCLSGFMGMDIPAPAGPLWILGDVFIGRFYSVFDHG 385

  Fly   383 NDRVGFADAK 392
            |.|||||.::
 Worm   386 NKRVGFATSR 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cathD	NP_001334713.1	None
asp-3	NP_509142.2	pepsin_retropepsin_like	59..393	CDD:299705	168/334 (50%)
		Asp	68..393	CDD:278455	163/325 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100536
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3883
SonicParanoid	1	1.000	-	-		X163
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.820