Protein Alignment cathD and asp-14

DIOPT Version :10

• Sequence 1: NP_652013.1
• Gene: cathD / 45268
• FlyBaseID: FBgn0029093
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: NP_509082.2
• Gene: asp-14 / 180917
• WormBaseID: WBGene00019619
• Length: 366
• Species: Caenorhabditis elegans
• Alignment Length: 406
• Identity: 101/406 - (24%)
• Similarity: 164/406 - (40%)
• Gaps: 68/406 - (16%)

  Fly     6 LLLVAFLAAAVAHPNSQEKPGLLRVPLHKFQSARRHFADVGTELQQLRIRYGGGDVPEPLSNYMD 70
            :||:||:|:..|          ..:|. |..:|..:...             ||...|..|.:..
 Worm     5 ILLLAFVASTSA----------FVIPF-KVHAAVTNITK-------------GGQTLEQTSTFFV 45

  Fly    71 AQYYGPIAIGSPPQNFRVVFDTGSSNLWVPSKKCHLTNIACLMHNKYDASKSKTYTKNGTEFAIQ 135
            |.    :.:|:|.|.|.||.||.::::.:|...|...| .|....:::.:||.:|...|.::..:
 Worm    46 AN----LTMGTPGQLFTVVIDTSTADIVIPDMSCKTAN-NCYNKRRFNQAKSSSYYAYGNKYTYK 105

  Fly   136 YGSGSLSGYLSTDTVSIAGLDIKDQTFAEALSEPGLVFVAAK----------FDGILGLGYNSIS 190
            ...|:..|:.:.|||.|.  |.|    .:.::.||:.|:.|.          .|||||||:.:.|
 Worm   106 NNLGTFQGFDAKDTVVIG--DRK----TDLITIPGVKFMQATDLGLLMDGLGADGILGLGFTASS 164

  Fly   191 VDKVKPPFYAMYEQGLISAPVFSFYL---NRDPASPEGGEIIFGGSDPNHYTGEFTYLPVTRKAY 252
            ......||......|.||...:|.:|   |:.......|.|.:||.||.|.....||:|:.....
 Worm   165 QIGGNSPFVQGVNAGDISGTFYSIWLEHFNQTDDLGTHGVIYYGGFDPVHCAPNPTYVPLASAYA 229

  Fly   253 WQIKMDAASIGDLQLCKGG---CQVIADTGTSLIAAPLEEATSINQKIG-GTPIIGGQY--VVSC 311
            :|:.|.:..:.........   .|...||.|:.|..|....:.:...:| .|.::...|  :|.|
 Worm   230 YQLTMSSFKVVGSSATNSNNKYIQTYLDTTTAQIGLPKTYISQVFDSLGISTNVMNAIYPTIVPC 294

  Fly   312 DLIPQLPVIKFVLGGKTFELEGKDYILRVAQMGKTICLSGFMGLDIPPPNGPLWILG-DVFIGKY 375
            :  .::.:....:.|.|..:..:|.:         |...|...|.|.|....: ||| .::.|:
 Worm   295 N--TKITLTFGFVSGTTVSITERDLV---------ISFFGTCRLQIIPTTDRI-ILGLPLYRGR- 346

  Fly   376 YTEFDMGNDRVGFADA 391
            .|.||....||||..|
 Worm   347 CTYFDPIMQRVGFTPA 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cathD	NP_652013.1	A1_Propeptide	29..56	CDD:462326	3/26 (12%)
		pepsin_retropepsin_like	62..389	CDD:472175	88/346 (25%)
asp-14	NP_509082.2	pepsin_like	44..361	CDD:133138	87/340 (26%)