Protein Alignment cathD and Napsa

DIOPT Version :10

• Sequence 1: NP_652013.1
• Gene: cathD / 45268
• FlyBaseID: FBgn0029093
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: NP_032463.1
• Gene: Napsa / 16541
• MGIID: 109365
• Length: 419
• Species: Mus musculus
• Alignment Length: 402
• Identity: 195/402 - (48%)
• Similarity: 255/402 - (63%)
• Gaps: 15/402 - (3%)

  Fly     1 MQKVALLLVAFLAAAVAHPNSQEKPGLLRVPLHKFQSARRHFADVG--TELQQL-RIRYGGGDVP 62
            |..:.|||:..|...:    ..|:..|:||||.:.....|....:.  .:|.:| |....||: |
Mouse     1 MSPLLLLLLCLLLGNL----EPEEAKLIRVPLQRIHLGHRILNPLNGWEQLAELSRTSTSGGN-P 60

  Fly    63 E--PLSNYMDAQYYGPIAIGSPPQNFRVVFDTGSSNLWVPSKKCHLTNIACLMHNKYDASKSKTY 125
            .  |||.:|:.||:|.|.:|:|||||.||||||||||||||.:||..::||..|::::...|.::
Mouse    61 SFVPLSKFMNTQYFGTIGLGTPPQNFTVVFDTGSSNLWVPSTRCHFFSLACWFHHRFNPKASSSF 125

  Fly   126 TKNGTEFAIQYGSGSLSGYLSTDTVSIAGLDIKDQTFAEALSEPGLVFVAAKFDGILGLGYNSIS 190
            ..|||:||||||:|.|||.||.|.::|.|:.....||.|||.||.|:|..|.||||||||:.:::
Mouse   126 RPNGTKFAIQYGTGRLSGILSQDNLTIGGIHDAFVTFGEALWEPSLIFALAHFDGILGLGFPTLA 190

  Fly   191 VDKVKPPFYAMYEQGLISAPVFSFYLNRDPASPEGGEIIFGGSDPNHYTGEFTYLPVTRKAYWQI 255
            |..|:||..||.||||:..||||||||||....:|||::.|||||.||....|::|||..||||:
Mouse   191 VGGVQPPLDAMVEQGLLEKPVFSFYLNRDSEGSDGGELVLGGSDPAHYVPPLTFIPVTIPAYWQV 255

  Fly   256 KMDAASIG-DLQLCKGGCQVIADTGTSLIAAPLEEATSINQKIGGTPIIGGQYVVSCDLIPQLPV 319
            .|::..:| .|.||..||..|.|||||||..|.||..::|:.|||.|.:.|||.:.|...|.||.
Mouse   256 HMESVKVGTGLSLCAQGCSAILDTGTSLITGPSEEIRALNKAIGGYPFLNGQYFIQCSKTPTLPP 320

  Fly   320 IKFVLGGKTFELEGKDYILRVAQMGKTICLSGFMGLDIPPPNGPLWILGDVFIGKYYTEFDMGN- 383
            :.|.|||..|.|.|:||::::.|....:||.||..||||.|.||||||||||:|.|...||.|:
Mouse   321 VSFHLGGVWFNLTGQDYVIKILQSDVGLCLLGFQALDIPKPAGPLWILGDVFLGPYVAVFDRGDK 385

  Fly   384 ---DRVGFADAK 392
               .|||.|.|:
Mouse   386 NVGPRVGLARAQ 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cathD	NP_652013.1	A1_Propeptide	29..56	CDD:462326	8/29 (28%)
		pepsin_retropepsin_like	62..389	CDD:472175	176/333 (53%)
Napsa	NP_032463.1	pepsin_retropepsin_like	68..394	CDD:472175	172/325 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	391..419		4/7 (57%)