Protein Alignment cathD and Ctse

DIOPT Version :9

• Sequence 1: NP_001334713.1
• Gene: cathD / 45268
• FlyBaseID: FBgn0029093
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: NP_031825.2
• Gene: Ctse / 13034
• MGIID: 107361
• Length: 397
• Species: Mus musculus
• Alignment Length: 403
• Identity: 187/403 - (46%)
• Similarity: 247/403 - (61%)
• Gaps: 27/403 - (6%)

  Fly     4 VALLLVAFLAAAVAHPNSQEKPGLLRVPLHKFQSARR--------------HFADVGTELQQLRI 54
            :.|||:..|..|      |.:..|.||||.:.||.|:              |..|: |.|.:...
Mouse     5 LVLLLLLLLDLA------QAQGALHRVPLRRHQSLRKKLRAQGQLSEFWRSHNLDM-TRLSESCN 62

  Fly    55 RYGGGDVPEPLSNYMDAQYYGPIAIGSPPQNFRVVFDTGSSNLWVPSKKCHLTNIACLMHNKYDA 119
            .|  ..|.|||.||:|.:|:|.|:||:|||||.|:||||||||||||..|  |:.||..|..:..
Mouse    63 VY--SSVNEPLINYLDMEYFGTISIGTPPQNFTVIFDTGSSNLWVPSVYC--TSPACKAHPVFHP 123

  Fly   120 SKSKTYTKNGTEFAIQYGSGSLSGYLSTDTVSIAGLDIKDQTFAEALSEPGLVFVAAKFDGILGL 184
            |:|.|||:.|..|:||||:|||:|.:..|.||:.||.:..|.|.|::.|||..||.|:|||||||
Mouse   124 SQSDTYTEVGNHFSIQYGTGSLTGIIGADQVSVEGLTVDGQQFGESVKEPGQTFVNAEFDGILGL 188

  Fly   185 GYNSISVDKVKPPFYAMYEQGLISAPVFSFYLNRDPASPEGGEIIFGGSDPNHYTGEFTYLPVTR 249
            ||.|::...|.|.|..|..|.|::.|:||.||:.||....|.|:.|||.||:|::|...::|||:
Mouse   189 GYPSLAAGGVTPVFDNMMAQNLVALPMFSVYLSSDPQGGSGSELTFGGYDPSHFSGSLNWIPVTK 253

  Fly   250 KAYWQIKMDAASIGD-LQLCKGGCQVIADTGTSLIAAPLEEATSINQKIGGTPIIGGQYVVSCDL 313
            :|||||.:|...:|| :..|..|||.|.|||||||..|.::...:.:.||.|| |.|:|.|.|..
Mouse   254 QAYWQIALDGIQVGDTVMFCSEGCQAIVDTGTSLITGPPDKIKQLQEAIGATP-IDGEYAVDCAT 317

  Fly   314 IPQLPVIKFVLGGKTFELEGKDYILRVAQMGKTICLSGFMGLDIPPPNGPLWILGDVFIGKYYTE 378
            :..:|.:.|::...::.|...||||.....|...|.|||.|||||||.|||||||||||.::|:.
Mouse   318 LDTMPNVTFLINEVSYTLNPTDYILPDLVEGMQFCGSGFQGLDIPPPAGPLWILGDVFIRQFYSV 382

  Fly   379 FDMGNDRVGFADA 391
            ||.||::||.|.|
Mouse   383 FDRGNNQVGLAPA 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cathD	NP_001334713.1	None
Ctse	NP_031825.2	A1_Propeptide	22..50	CDD:285240	8/27 (30%)
		Asp	78..395	CDD:278455	160/319 (50%)
		pepsin_retropepsin_like	79..394	CDD:299705	159/317 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S917
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100536
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X163
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.780