Protein Alignment cathD and nots

DIOPT Version :9

• Sequence 1: NP_001334713.1
• Gene: cathD / 45268
• FlyBaseID: FBgn0029093
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: NP_571879.1
• Gene: nots / 114367
• ZFINID: ZDB-GENE-010620-1
• Length: 416
• Species: Danio rerio
• Alignment Length: 413
• Identity: 171/413 - (41%)
• Similarity: 237/413 - (57%)
• Gaps: 34/413 - (8%)

  Fly     1 MQKVALLLVAFLAAAVAHPNSQEKPGLLRVPLHKFQSAR---RHFADVGTELQQ-----LRIRY- 56
            |:...|:|:..|....:       .|||||.|.::.|.|   |..|.:...|:|     ...||
Zfish     1 MRSAGLILILVLHLGFS-------TGLLRVALRQYPSVRSRLRASAQLEEFLKQHQPDMFSRRYV 58

  Fly    57 -----------GGGDVPEPLSNYMDAQYYGPIAIGSPPQNFRVVFDTGSSNLWVPSKKCHLTNIA 110
                       .|..|.|.|.|:||||::|.|::|.|.|||.||||||||:|||||..|  ...|
Zfish    59 QCFPPAQHFLRPGRRVTERLYNFMDAQFFGQISLGRPEQNFTVVFDTGSSDLWVPSSYC--VTQA 121

  Fly   111 CLMHNKYDASKSKTYTKNGTEFAIQYGSGSLSGYLSTDTVSIAGLDIKDQTFAEALSEPGLVFVA 175
            |.:|||:.|.:|.|||.:|..|.|.||||.|.|.::.|.:.:..:.:::|.|.||:.|||..||.
Zfish   122 CALHNKFKAFESSTYTHDGRVFGIHYGSGHLLGVMARDELKVGSVRVQNQVFGEAVYEPGFSFVL 186

  Fly   176 AKFDGILGLGYNSISVDKVKPPFYAMYEQGLISAPVFSFYLNRDPASPEGGEIIFGGSDPNHYTG 240
            |:|||:||||:..::.:|..|.|..|.||.::..|||||||..: .|..|||::||.:|.:.:..
Zfish   187 AQFDGVLGLGFPQLAEEKGSPVFDTMMEQNMLDQPVFSFYLTNN-GSGFGGELVFGANDESRFLP 250

  Fly   241 EFTYLPVTRKAYWQIKMDAASI-GDLQLCK---GGCQVIADTGTSLIAAPLEEATSINQKIGGTP 301
            ...::|||:|.|||||:||..: |.|....   .|||.|.|||||||..|..:...:.|.||.||
Zfish   251 PINWIPVTQKGYWQIKLDAVKVQGALSFSDRSVQGCQAIVDTGTSLIGGPARDILILQQFIGATP 315

  Fly   302 IIGGQYVVSCDLIPQLPVIKFVLGGKTFELEGKDYILRVAQMGKTICLSGFMGLDIPPPNGPLWI 366
            ...|::||.|..:..|||:.|::....:.|.|:.|:.|.....|.||.|||..:::|.|.||:||
Zfish   316 TANGEFVVDCVRVSSLPVVSFLINSVEYSLSGEQYVRRETLNNKQICFSGFQSIEVPSPAGPVWI 380

  Fly   367 LGDVFIGKYYTEFDMGNDRVGFA 389
            |||||:.:.|:.:|.|.:|||.|
Zfish   381 LGDVFLSQVYSIYDRGENRVGLA 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cathD	NP_001334713.1	None
nots	NP_571879.1	A1_Propeptide	20..48	CDD:285240	10/27 (37%)
		Asp	85..403	CDD:278455	144/320 (45%)
		pepsin_retropepsin_like	86..403	CDD:299705	143/319 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100536
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.930