Protein Alignment cathD and LOC101733630

DIOPT Version :10

• Sequence 1: NP_652013.1
• Gene: cathD / 45268
• FlyBaseID: FBgn0029093
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: XP_012817292.3
• Gene: LOC101733630 / 101733630
• XenbaseID: XB-GENE-29087091
• Length: 343
• Species: Xenopus tropicalis
• Alignment Length: 326
• Identity: 211/326 - (64%)
• Similarity: 252/326 - (77%)
• Gaps: 1/326 - (0%)

  Fly    68 YMDAQYYGPIAIGSPPQNFRVVFDTGSSNLWVPSKKCHLTNIACLMHNKYDASKSKTYTKNGTEF 132
            |:.|||||.|.:|||||||.||||||||||||||..|.:.:|||.||:|||:|||.||.||||.|
 Frog    18 YLQAQYYGEIGLGSPPQNFTVVFDTGSSNLWVPSVHCSMLDIACWMHHKYDSSKSSTYVKNGTAF 82

  Fly   133 AIQYGSGSLSGYLSTDTVSIAGLDIKDQTFAEALSEPGLVFVAAKFDGILGLGYNSISVDKVKPP 197
            |||||:||||||||.|||:|..|.:|.|.|.||:.:||:.|||||||||||:.|..||||.|.|.
 Frog    83 AIQYGTGSLSGYLSKDTVTIGNLAVKGQMFGEAVKQPGVTFVAAKFDGILGMAYPVISVDGVPPV 147

  Fly   198 FYAMYEQGLISAPVFSFYLNRDPASPEGGEIIFGGSDPNHYTGEFTYLPVTRKAYWQIKMDAASI 262
            |..:..|.|:.:.:|||||||:|.:..|||::.||:||.:|||:|.||.|||||||||.||...:
 Frog   148 FDNIMAQKLVESNIFSFYLNRNPDTQPGGELLLGGTDPKYYTGDFHYLNVTRKAYWQIHMDQLGV 212

  Fly   263 GD-LQLCKGGCQVIADTGTSLIAAPLEEATSINQKIGGTPIIGGQYVVSCDLIPQLPVIKFVLGG 326
            || |.||||||:||.|||||||..||||.|::.:.||..|:|.|||:|.||.:|.||||...|||
 Frog   213 GDQLTLCKGGCEVIVDTGTSLITGPLEEVTALQKAIGAVPLIQGQYMVQCDKVPTLPVISLTLGG 277

  Fly   327 KTFELEGKDYILRVAQMGKTICLSGFMGLDIPPPNGPLWILGDVFIGKYYTEFDMGNDRVGFADA 391
            :.:.|.|:.||::|:|.|.||||||||||:||||.||||||||||||:||:.||...||||||.|
 Frog   278 QVYTLTGEQYIMKVSQRGSTICLSGFMGLNIPPPAGPLWILGDVFIGQYYSVFDRAYDRVGFAKA 342

  Fly   392 K 392
            |
 Frog   343 K 343

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cathD	NP_652013.1	A1_Propeptide	29..56	CDD:462326
		pepsin_retropepsin_like	62..389	CDD:472175	207/321 (64%)
LOC101733630	XP_012817292.3	Cathepsin_D2	18..341	CDD:133157	208/322 (65%)