DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment deltaCOP and AT5G05010

DIOPT Version :9

Sequence 1:	NP_652012.1	Gene:	deltaCOP / 45250	FlyBaseID:	FBgn0028969	Length:	532	Species:	Drosophila melanogaster
Sequence 2:	NP_001031836.1	Gene:	AT5G05010 / 830383	AraportID:	AT5G05010	Length:	527	Species:	Arabidopsis thaliana

Alignment Length:	546	Identity:	223/546 - (40%)
Similarity:	339/546 - (62%)	Gaps:	33/546 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVLIAAAVCTKNGKVILSRQFVEMTKARIEGLLAAFPKLMTAGKQHTYVETDSVRYVYQPMEKLY 65
            ||::|||:..|:||||:||.:|:|::.||||||||||||:..||||||:||::|||||||:|.|:
plant     1 MVVLAAAIVVKSGKVIVSRHYVDMSRIRIEGLLAAFPKLVGMGKQHTYIETENVRYVYQPIEALF 65

  Fly    66 MLLITTKASNILEDLETLRLFSKVIPEYSHSLDEKEIVENAFNLIFAFDEIVALGYRESVNLAQI 130
            :||:|||.|||||||.||.|.||::||||.||||:.|...:|.|||||||:::||::|||.:||:
plant    66 LLLVTTKQSNILEDLATLTLLSKLVPEYSMSLDEEGISRASFELIFAFDEVISLGHKESVTVAQV 130

  Fly   131 KTFVEMDSHEEKVYQAVRQTQERDARQKMREKAKELQRQRMEASKRGG-PSLGGIGS--RSGGFS 192
            |.:.||:|||||:::.|.|::..|.:..|:.||.|:.:.::|.:|.|| .|:|.:||  ...||:
plant   131 KQYCEMESHEEKLHKLVMQSKINDTKDVMKRKANEIDKSKIEKNKPGGFSSMGSMGSGRLESGFN 195

  Fly   193 ADGIGSSGVSSSSGASSANTGITSID-VDTK----SKAAASKPASRNALKLGGKSKDVDSFVDQL 252
            ...| |||.....|:.|....|:.:| ::||    |:::.:.|...:.:|||...|  :..::.|
plant   196 ELSI-SSGGGGGYGSGSGFGMISDVDPINTKPKDRSRSSVTAPPKSSGMKLGKSGK--NQLMESL 257

  Fly   253 KNEGEKIANLAPAAPAGGSSAAASASAAAKAAIASDIHKESVHLKIEDKLVVRLGRDGGVQQFEN 317
            |.|||.:  :....|.|.|.|||....            :...|.:|:||.|.|.||||:..|:.
plant   258 KAEGEDV--IEDVKPTGQSKAAAPPPT------------DPFTLTVEEKLNVALRRDGGLSSFDM 308

  Fly   318 SGLLTLRITDEAYGRILLKLSPNHTQGLQLQTHPNVDKELFKSRTTIGLKNLGKPFPL---NTDV 379
            .|.|:|:|.::..|.:.::::......:..:||||:::::|.:...:|||...:|||.   ...|
plant   309 QGTLSLQILNQEDGFVQVQIATGENPEILFKTHPNINRDMFNNENILGLKRPDQPFPTGQGGDGV 373

  Fly   380 GVLKWRFVSQDESAVPLTINCWPSDNGEGGCDVNIEYELEAQQLELQDVAIVIPLP-MNVQPSVA 443
            |:|:||....|||.||||||||||.:| ....|::||| .:...:|.:|.|.:||| :...|||.
plant   374 GLLRWRMQRADESMVPLTINCWPSVSG-NETYVSLEYE-ASSMFDLTNVIISVPLPALREAPSVR 436

  Fly   444 EYDGTYNYDSRKHVLQWHIPIIDAANKSGSMEFSCSASIPGDFFPLQVSFVSKTPYAGVVAQDVV 508
            :.||.:.||.|..||:|.|.:||.:|:||||||.........|||:.|.|.:.:.|:|:....::
plant   437 QCDGEWRYDPRNSVLEWSILLIDNSNRSGSMEFVVPPVDSSVFFPISVQFAATSTYSGLKVTGMI 501

  Fly   509 QV--DSEAAVKYSSESILFVEKYEIV 532
            .:  ...|..::...:.|..:.|:::
plant   502 PLRGGGGATPRFVQRTQLIAQNYQVI 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
deltaCOP	NP_652012.1	AP_delta-COPI_MHD	292..529	CDD:271162	86/242 (36%)
AT5G05010	NP_001031836.1	Delta_COP_N	4..133	CDD:341434	83/128 (65%)
AT5G05010	NP_001031836.1	AP_delta-COPI_MHD	283..524	CDD:271162	86/242 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	147	1.000	Domainoid score	I1455
eggNOG	1	0.900	-	-		E1_KOG2635
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1250
Inparanoid	1	1.050	394	1.000	Inparanoid score	I489
OMA	1	1.010	-	-		QHG54088
OrthoDB	1	1.010	-	-		D1027200at2759
OrthoFinder	1	1.000	-	-		FOG0003612
OrthoInspector	1	1.000	-	-		oto3866
orthoMCL	1	0.900	-	-		OOG6_101729
Panther	1	1.100	-	-	LDO	PTHR10121
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2487
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840