Protein Alignment deltaCOP and ARCN1

DIOPT Version :10

• Sequence 1: NP_652012.1
• Gene: deltaCOP / 45250
• FlyBaseID: FBgn0028969
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_001412002.1
• Gene: ARCN1 / 372
• HGNCID: 649
• Length: 532
• Species: Homo sapiens
• Alignment Length: 554
• Identity: 309/554 - (55%)
• Similarity: 385/554 - (69%)
• Gaps: 44/554 - (7%)

  Fly     1 MVLIAAAVCTKNGKVILSRQFVEMTKARIEGLLAAFPKLMTAGKQHTYVETDSVRYVYQPMEKLY 65
            |||:|||||||.||.|:||||||||:.|||||||||||||..|||||:|||:|||||||||||||
Human     1 MVLLAAAVCTKAGKAIVSRQFVEMTRTRIEGLLAAFPKLMNTGKQHTFVETESVRYVYQPMEKLY 65

  Fly    66 MLLITTKASNILEDLETLRLFSKVIPEYSHSLDEKEIVENAFNLIFAFDEIVALGYRESVNLAQI 130
            |:|||||.||||||||||||||:|||||..:|:|.||.|:.|:|||||||||||||||:||||||
Human    66 MVLITTKNSNILEDLETLRLFSRVIPEYCRALEENEISEHCFDLIFAFDEIVALGYRENVNLAQI 130

  Fly   131 KTFVEMDSHEEKVYQAVRQTQERDARQKMREKAKELQRQRMEASKRGGPSLGGIGSRSGGFSADG 195
            :||.|||||||||::|||:||||:|:.:||.||||||:.|.:|.::        |.::.||.  |
Human   131 RTFTEMDSHEEKVFRAVRETQEREAKAEMRRKAKELQQARRDAERQ--------GKKAPGFG--G 185

  Fly   196 IGSSGVSSSSGASSANTGITSIDVDTKSKAAASKPASRNALKLGGKSKDVDSFVDQLKNEGEKIA 260
            .|||.||..|.|:.....|...|....:.|.|.......|||||.|.|:||:|||:||:|||.|.
Human   186 FGSSAVSGGSTAAMITETIIETDKPKVAPAPARPSGPSKALKLGAKGKEVDNFVDKLKSEGETIM 250

  Fly   261 NLAPAAPAGGSSAAASASAAAKAAIASDIHKESVHLKIEDKLVVRLGRDGGVQQFENSGLLTLRI 325
                      ||:....::.|....|..|:.||||:|||:|:.:..|||||:|..|..|::.|||
Human   251 ----------SSSMGKRTSEATKMHAPPINMESVHMKIEEKITLTCGRDGGLQNMELHGMIMLRI 305

  Fly   326 TDEAYGRILLKLSPNHTQGLQLQTHPNVDKELFKSRTTIGLKNLGKPFPLNTDVGVLKWRFVSQD 390
            :|:.||||.|.:.....:|:||||||||||:||.:.:.|||||..|.||:|:||||||||..:.:
Human   306 SDDKYGRIRLHVENEDKKGVQLQTHPNVDKKLFTAESLIGLKNPEKSFPVNSDVGVLKWRLQTTE 370

  Fly   391 ESAVPLTINCWPSDNGEGGCDVNIEYELEAQQLELQDVAIVIPLPMNVQ---------------- 439
            ||.:|||||||||::| .||||||||||:...|||.||.|.||||...:
Human   371 ESFIPLTINCWPSESG-NGCDVNIEYELQEDNLELNDVVITIPLPTGTKIGTIQRRLAWALCKAD 434

  Fly   440 ------PSVAEYDGTYNYDSRKHVLQWHIPIIDAANKSGSMEFSCSASIPGDFFPLQVSFVSKTP 498
                  |.:.|.||.|.:|||::.|:|.:|:|||.|||||:|||. |..|.||||:|||||||..
Human   435 MSGVGAPVIGEIDGEYRHDSRRNTLEWCLPVIDAKNKSGSLEFSI-AGQPNDFFPVQVSFVSKKN 498

  Fly   499 YAGVVAQDVVQVDSEAAVKYSSESILFVEKYEIV 532
            |..:....|.|||..:.|::|:|:...|:||||:
Human   499 YCNIQVTKVTQVDGNSPVRFSTETTFLVDKYEIL 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
deltaCOP	NP_652012.1	Delta_COP_N	4..133	CDD:341434	104/128 (81%)
		AP_delta-COPI_MHD	292..529	CDD:271162	131/258 (51%)
ARCN1	NP_001412002.1	None