DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment deltaCOP and ret2

DIOPT Version :9

Sequence 1:	NP_652012.1	Gene:	deltaCOP / 45250	FlyBaseID:	FBgn0028969	Length:	532	Species:	Drosophila melanogaster
Sequence 2:	NP_588336.1	Gene:	ret2 / 2538953	PomBaseID:	SPCC285.08	Length:	240	Species:	Schizosaccharomyces pombe

Alignment Length:	248	Identity:	97/248 - (39%)
Similarity:	159/248 - (64%)	Gaps:	22/248 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVLIAAAVCTKNGKVILSRQFVEMTKARIEGLLAAFPKLMTAGKQHTYVETDSVRYVYQPMEKLY 65
            ||::|.::..:.||.|:||||.||::.|:|.||::||.|::...|:|.||:|:||:||||:::||
pombe     1 MVVLAVSIVNRGGKAIISRQFREMSRVRVESLLSSFPALVSEKSQNTTVESDNVRFVYQPLDELY 65

  Fly    66 MLLITTKASNILEDLETLRLFSKVIPEYSHSLDEKEIVENAFNLIFAFDEIVALGYRESVNLAQI 130
            ::|||...||||:|::||.|.|:|:.....||:|:||:|.||.:..||||..:||||::|:|.||
pombe    66 IVLITNLQSNILQDIDTLHLLSQVVTSICSSLEEREILEYAFEIFTAFDEATSLGYRDNVSLTQI 130

  Fly   131 KTFVEMDSHEEKVYQAVRQTQERDARQKMREKAKELQRQRMEASKRGGPSLGGIGSRSGGFSADG 195
            ||::||:|||||:.:.|.:.:|.:|.::.:.:.|:|:.|:.||::|               :|..
pombe   131 KTYLEMESHEEKIQEIVSRNKEIEATEERKRRIKQLELQKKEAARR---------------AAQN 180

  Fly   196 IGSSGVSSSSGASSANTGITSIDVDTKS-------KAAASKPASRNALKLGGK 241
            :.|:....|.|..:.||...:.:|:.:|       .|.||.......::||.|
pombe   181 LPSADAYESIGYQTVNTTFATSNVEDESAMESYHAAAKASSAPKAKGMQLGKK 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
deltaCOP	NP_652012.1	AP_delta-COPI_MHD	292..529	CDD:271162
ret2	NP_588336.1	Clat_adaptor_s	3..136	CDD:261170	65/132 (49%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	138	1.000	Domainoid score	I1234
eggNOG	1	0.900	-	-		E1_KOG2635
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003612
OrthoInspector	1	1.000	-	-		oto101238
orthoMCL	1	0.900	-	-		OOG6_101729
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R228
SonicParanoid	1	1.000	-	-		X2487
TreeFam	0	0.000	Not matched by this tool.
	8	7.740