DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eEF1beta and Cars

DIOPT Version :9

Sequence 1:	NP_001286506.1	Gene:	eEF1beta / 45249	FlyBaseID:	FBgn0028737	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_038770.3	Gene:	Cars / 27267	MGIID:	1351477	Length:	831	Species:	Mus musculus

Alignment Length:	296	Identity:	71/296 - (23%)
Similarity:	116/296 - (39%)	Gaps:	107/296 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LKELNAFLADNSYISGYTPSKADLSVFDALGKAPSADN--VNVARWYRHI--------------- 59
            ::.|:..|:..|||.||:.|:||:.||..| .||.||:  .:||||:|||
Mouse    25 VQALDQHLSTRSYIQGYSLSQADVDVFRQL-SAPPADSRLFHVARWFRHIEALLGGPQGRDEPCR 88

  Fly    60 --ASFEAAERAAWS---GTP-----------------LPQLAGGK--------PTVAAAA----- 89
              ||.....:..||   ||.                 :||  .||        |||..|:
Mouse    89 LQASKGRRVQPQWSPPAGTEPCRLRLYNSLTRNKDVFIPQ--DGKKVTWYCCGPTVYDASHMGHA 151

  Fly    90 ---------KPAADDDDDVDLF---GSDDEEDEEAERIKQERV-AAYAAKKSKKPALIAKSSVLL 141
                     :....|....|:|   ...|.:|:...|.:|..: ..|  ::.|.||    :.:|.
Mouse   152 RSYISFDILRRVLRDYFQYDVFYCMNITDIDDKIIRRARQNYLFEQY--REQKPPA----TQLLK 210

  Fly   142 DV----KPW----DDETD------MKEMENNVRTIEMDGLLWGASKLVPVGYGINKLQIMCVIED 192
            ||    ||:    .:.||      ::.::|:|:.         |::  |:...: :..:.....|
Mouse   211 DVRDAMKPFSVKLSETTDPDKRQMLERIQNSVKL---------ATE--PLEQAV-RSSLSGEEVD 263

  Fly   193 DKVSIDLLQEKIEEFEDFVQS------VDIAAFNKI 222
            .||.: ||:|..:...|::.|      .|.:.|:|:
Mouse   264 SKVQV-LLEEAKDLLSDWLDSTGGSEVTDNSIFSKL 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eEF1beta	NP_001286506.1	GST_C_eEF1b_like	<3..62	CDD:198341	25/68 (37%)
eEF1beta	NP_001286506.1	EF1_GNE	139..222	CDD:279125	21/102 (21%)
Cars	NP_038770.3	GST_C_CysRS_N	4..76	CDD:198343	24/51 (47%)
		PTZ00399	91..827	CDD:240402	47/229 (21%)
		CysRS_core	113..528	CDD:173899	41/207 (20%)
		'HIGH' region	140..150		4/9 (44%)
		'KMSKS' region	489..493
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	736..766
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2092
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810