DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment eEF1beta and EEF1D

DIOPT Version :9

Sequence 1:	NP_001286506.1	Gene:	eEF1beta / 45249	FlyBaseID:	FBgn0028737	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_001123525.3	Gene:	EEF1D / 1936	HGNCID:	3211	Length:	647	Species:	Homo sapiens

Alignment Length:	152	Identity:	100/152 - (65%)
Similarity:	126/152 - (82%)	Gaps:	5/152 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 TPLPQLAGGKPTVAAAAKPAADD-DDDVDLFGSD-DEEDEEAERIKQERVAAYAAKKSKKPALIA 135
            :|:.|:   :|.....|.||.|| |||:|||||| :|||:||.::::||:..||.||:|||||:|
Human   499 SPMRQV---EPPAKKPATPAEDDEDDDIDLFGSDNEEEDKEAAQLREERLRQYAEKKAKKPALVA 560

  Fly   136 KSSVLLDVKPWDDETDMKEMENNVRTIEMDGLLWGASKLVPVGYGINKLQIMCVIEDDKVSIDLL 200
            |||:|||||||||||||.::|..||:|::|||:|||||||||||||.||||.||:|||||..|||
Human   561 KSSILLDVKPWDDETDMAQLEACVRSIQLDGLVWGASKLVPVGYGIRKLQIQCVVEDDKVGTDLL 625

  Fly   201 QEKIEEFEDFVQSVDIAAFNKI 222
            :|:|.:||:.||||||||||||
Human   626 EEEITKFEEHVQSVDIAAFNKI 647

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eEF1beta	NP_001286506.1	GST_C_eEF1b_like	<3..62	CDD:198341
eEF1beta	NP_001286506.1	EF1_GNE	139..222	CDD:279125	61/82 (74%)
EEF1D	NP_001123525.3	EF-1_beta_acid	525..552	CDD:371151	14/26 (54%)
EEF1D	NP_001123525.3	EF1_GNE	564..647	CDD:376378	61/82 (74%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159540
Domainoid	1	1.000	137	1.000	Domainoid score	I4899
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1464823at2759
OrthoFinder	1	1.000	-	-		FOG0001111
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X680
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	7	6.810