Protein Alignment Nckx30C and Slc24a3

DIOPT Version :9

• Sequence 1: NP_652011.3
• Gene: Nckx30C / 45248
• FlyBaseID: FBgn0028704
• Length: 881
• Species: Drosophila melanogaster
• Sequence 2: NP_001343426.1
• Gene: Slc24a3 / 94249
• MGIID: 2137513
• Length: 645
• Species: Mus musculus
• Alignment Length: 623
• Identity: 223/623 - (35%)
• Similarity: 331/623 - (53%)
• Gaps: 101/623 - (16%)

  Fly   302 INDT---------HNDNSTTTKTPLFPKDLFTKEQLENGAVILHIIGVIYMFVALAIVCDEFFVP 357
            :|||         .:.|.|......||:|:|:.|....|||:||::..:|||.|||||||:||||
Mouse    69 VNDTLTSEDAGLQSSKNCTEPALHEFPRDIFSNEDRRQGAVVLHVLCAMYMFYALAIVCDDFFVP 133

  Fly   358 SLDVIIEKLGITDDVAGATFMAAGGSAPELFTSVIGVFVSFDDVGIGTIVGSAVFNILFVIGMCA 422
            ||:.|.|:|.:::|||||||||||.|||||||||||||::..|||:||||||||||||.:||:|.
Mouse   134 SLEKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCG 198

  Fly   423 LFSKTVLSLTWWPLFRDCSFYSISLLVLIYFFRDNRIFWWEALILFTIYIGYVAFMKWNVQVETC 487
            ||:..|::|:.|.|.||..:|::|::.||.|..|.::.|||:|:|..:|:.|:..||:|..:..|
Mouse   199 LFAGQVVALSSWCLLRDSIYYTLSVVALIVFIYDEKVSWWESLVLVLMYLIYIVIMKYNACIHQC 263

  Fly   488 VKKMITKNKVTRVRSTDQLMPAGNAANSSETSMATQPGGSVTSRAASETRSGPPGSSNAGATGNS 552
            .::. ||.             |||..|                           |.:|.....:|
Mouse   264 FERR-TKG-------------AGNMVN---------------------------GLANNAEIDDS 287

  Fly   553 SGGGGTSGSTQTGAKFRHGLLQLMIHTIDPLHDGKVDEKATQL-HAI----ASLKVLLDATKPQR 612
            |....|....:. |.|......:|           |||..:.. |.:    |.|::::.:..|.:
Mouse   288 SNCDATVVLLKK-ANFHRKASVIM-----------VDELLSAYPHQLSFSEAGLRIMITSHFPPK 340

  Fly   613 GGATTSAANHVKINLKETTLADR--PNGNIDTTLDSPSL----SGRRPSWIEQRVKIQTRKFSIK 671
              ...|.|:.:.||.::..:..|  .||..:..:..|..    :|..||....|....||:..|.
Mouse   341 --TRLSMASRMLINERQRLINSRAYTNGESEVAIKIPIKHTVENGTGPSSAPDRGVNGTRRDDIV 403

  Fly   672 A----------------------PEIEDEPE-PLSMAWPDTAR-KRLTYVLVAPLLVPMWLTLPD 712
            |                      .|.||:.| |.:...|.:.: :.:.:....||...::.|:|:
Mouse   404 AETDNETENENEDNENNENDEEEEEDEDDDEGPYTPFDPPSGKLETVKWAFTWPLSFVLYFTVPN 468

  Fly   713 TRTPRGKRFFPVTFIGSIVWIAAFSYLMVWWANVAGDTARIPPEVMGLTFLAAGTSIPDLITSVI 777
            ...|..:::|.|||..|.:|||||||:|||...:.|.|..||..:||:||||||||:||.:.|:|
Mouse   469 CNKPHWEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLI 533

  Fly   778 VARKGFGDMAVSSSVGSNIFDVTVGLPIPWLL--YGIIYGAPVEVNSVGMVCSITILFMMLVFVV 840
            |||:|.||||||:|:|||:||:.:||.:||.|  ..:.||:.:.:||.|::.|:.:|...:...|
Mouse   534 VARQGMGDMAVSNSIGSNVFDILIGLGLPWALQTLAVDYGSYIRLNSRGLIYSVGLLLASVFVTV 598

  Fly   841 MSIACFRWRMNKGLGFTMFLLYFAFVAVSLMFEYDVIT 878
            ..:...:|:::|.||.....||..|:..|:|.|::|.|
Mouse   599 FGVHLNKWQLDKKLGCGCLFLYGVFLCFSIMTEFNVFT 636

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nckx30C	NP_652011.3	Na_Ca_ex	336..480	CDD:279963	84/143 (59%)
		Na_Ca_ex	721..871	CDD:279963	70/151 (46%)
Slc24a3	NP_001343426.1	Na_Ca_ex	<89..631	CDD:332332	215/596 (36%)
		Alpha-1	148..188		33/39 (85%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	379..398		4/18 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	404..442		6/37 (16%)
		Alpha-2	520..551		21/30 (70%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000196
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810