DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Nckx30C and CCX4

DIOPT Version :9

Sequence 1:	NP_652011.3	Gene:	Nckx30C / 45248	FlyBaseID:	FBgn0028704	Length:	881	Species:	Drosophila melanogaster
Sequence 2:	NP_564650.1	Gene:	CCX4 / 841851	AraportID:	AT1G54115	Length:	644	Species:	Arabidopsis thaliana

Alignment Length:	591	Identity:	139/591 - (23%)
Similarity:	228/591 - (38%)	Gaps:	153/591 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   337 IIGV--IYMFVALAIVCDEFFVPSLDVIIEKLGITDDVAGATFMAAGGSAPELFTSVIGVFVSFD 399
            ::||  :.:|..|.....::|..||:.:.:.|.:...|||.|.:..|..||::|.| |..||..|
plant   139 LLGVWLVALFYLLGNTAADYFCCSLEKLSKLLRLPPTVAGVTLLPLGNGAPDVFAS-IAAFVGSD 202

  Fly   400 --DVGIGTIVGSAVFNILFVIGMCAL-FSKTVLSLTWWPLFRDCSFYSISLLVLIYFFRDNRIFW 461
              :||:.:::|.|||....|:|:.:| .:...:.:......||.||:..:|:.|:......::..
plant   203 KGEVGLNSVLGGAVFVTCVVVGIVSLCVADKEVKIDKKCFIRDLSFFLFTLVALMVILMVGKVTV 267

  Fly   462 WEALILFTIYIGYVAFMKWNVQVETCVKKMITK-NKVTRVRSTDQLMPAGNAANSSETSMATQPG 525
            ..|:...:||:.|.:.:..|        :::.| ::..::.|...|:|...:..||.:.....|.
plant   268 GIAIAFVSIYVFYASLVAAN--------EILRKHSRRLKLDSITPLLPMQGSVFSSPSVEEDIPM 324

  Fly   526 GSVTSRAASETRSGPPGSSNAGATGNSSGGGGTSGSTQTGAKFRHGLLQLMIHTIDPLHDGKVDE 590
            .|.....  :|..|||                                        .|||
plant   325 YSPLMEL--DTGEGPP----------------------------------------RLHD----- 342

  Fly   591 KATQLHAIASLKVLLDATKPQRGGATTSA--ANH-VKINLKETTLADRP--NGNIDTTLDSPSLS 650
                             :.||...||..|  :|| .|.|:.:   .:||  ....|......||.
plant   343 -----------------SLPQWMWATNVAIYSNHFAKANVHD---EERPPWGWTEDGAEVESSLC 387

  Fly   651 GRRPSWIEQRVKIQTRKFSIKAPEIEDEPEPLSMAWPDTARKRLTYVLVAPLLVP-MWLTLPDTR 714
            .:..|.:|..:.:..|   :..|.||::      :|..|  ..:..|.:||:|:. :|.:..||.
plant   388 SKITSLLETPLTVPRR---LTIPLIEED------SWSKT--YAVASVSLAPVLLSFLWSSQDDTS 441

  Fly   715 -TPRGKRFFPVTFIGSIVWIAAFS----------YLMVW----------W----AN--VA----- 747
             ..|...:|....|||.:...||.          ||:.|          |    ||  ||
plant   442 LQARIVAYFIGIAIGSTLGYLAFKNTEPDRPPQIYLIPWVLGGFIMSIVWFYMIANELVALLVTF 506

  Fly   748 GDTARIPPEVMGLTFLAAGTSIPDLITSVIVARKGFGD---MAVSSSVGSNIFDVTVGLPIPWLL 809
            |....|.|.::|||.||.|.|:.||::::.::..| ||   :|:|......:|:..|||.:...|
plant   507 GGIYGINPSILGLTVLAWGNSMGDLVSNIALSMNG-GDGVQIALSGCYAGPMFNTLVGLGMSMFL 570

  Fly   810 YGIIYGAPVEVNSVGMVCSITILFMMLVFVVMSIACFRW----------RMNKGLGFTMFLLYFA 864
                 ||..:.....|:.....||..|.|::..:.   |          |.||.:|..:..||..
plant   571 -----GAWSKSPETYMIPEDNSLFYTLGFLIFGLI---WSLVMLPRNEMRPNKVMGIGLITLYLI 627

  Fly   865 FVAVSL 870
            ||...|
plant   628 FVTFRL 633

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nckx30C	NP_652011.3	Na_Ca_ex	336..480	CDD:279963	40/147 (27%)
Nckx30C	NP_652011.3	Na_Ca_ex	721..871	CDD:279963	53/194 (27%)
CCX4	NP_564650.1	PLN03151	1..644	CDD:215604	139/591 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	70	1.000	Domainoid score	I3391
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	135	1.000	Inparanoid score	I1830
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.860