Protein Alignment Nckx30C and slc24a4a

DIOPT Version :9

• Sequence 1: NP_652011.3
• Gene: Nckx30C / 45248
• FlyBaseID: FBgn0028704
• Length: 881
• Species: Drosophila melanogaster
• Sequence 2: XP_005158898.1
• Gene: slc24a4a / 550467
• ZFINID: ZDB-GENE-050417-291
• Length: 621
• Species: Danio rerio
• Alignment Length: 595
• Identity: 218/595 - (36%)
• Similarity: 326/595 - (54%)
• Gaps: 87/595 - (14%)

  Fly   301 GINDTHNDNSTTTKTPLFPKDLFTKEQLENGAVILHIIGVIYMFVALAIVCDEFFVPSLDVIIEK 365
            |.|:|...|.|......||:||||.:|...|||:|||...:|||:|||||||::||.||:.|.||
Zfish    85 GDNETQEKNCTAPAIHEFPEDLFTNQQRSQGAVLLHIFAALYMFLALAIVCDDYFVTSLEKICEK 149

  Fly   366 LGITDDVAGATFMAAGGSAPELFTSVIGVFVSFDDVGIGTIVGSAVFNILFVIGMCALFSKTVLS 430
            |.:::|||||||||||.||||||.|:||||::..|||:||||||||||||.:||:|.:|:..|:.
Zfish   150 LHLSEDVAGATFMAAGSSAPELFASIIGVFITHGDVGVGTIVGSAVFNILCIIGVCGIFAGQVVF 214

  Fly   431 LTWWPLFRDCSFYSISLLVLIYFFRDNRIFWWEALILFTIYIGYVAFMKWNVQVETCVKKMITKN 495
            ||.:.:|||.|:|.||::.||.|..|:.|.|||:|:|..:|:||:..||:|    |.::.:....
Zfish   215 LTKYAVFRDSSYYIISVIALIVFIYDDEILWWESLVLIVMYLGYIIVMKFN----TSLQNLFNGK 275

  Fly   496 KVTRVRSTDQLMPAGNAANSSETSMATQPGGSVTSRAASETRSGPPGSSNAGATGNSSGGGGTSG 560
            :..||.:       |||.:|.     .:||.....:...:. |.|
Zfish   276 EDKRVTN-------GNAVSSE-----MEPGNDCFEQFWDDP-SWP-------------------- 307

  Fly   561 STQTGAKFRHGLLQLMIHTIDPLHDGKVDEKATQLHAIASLKVLLDATKPQ----RGGATTSAAN 621
                              .:.|:...|:..:.    ::..:..:::::.|.    ..|......|
Zfish   308 ------------------LLAPVKPNKIYTRG----SVVMVDEMMNSSPPHYRFPEAGLRVMITN 350

  Fly   622 HV--KINLK---------ETTLADRPNGNIDTTLDSPSLSGRRPSWIEQRVKIQTRKFSIKAPEI 675
            |.  |..|:         :..|....||     :||..:|.::...:|.. .:...|.|   .|.
Zfish   351 HFGPKTRLRMASRLIINEQQRLVKSANG-----VDSVLVSDQKADTMENG-NVAEDKLS---EEQ 406

  Fly   676 EDEPEPLSMAWPDTARKRLTYVLVAPLLVPMWLTLPDTRTPRGKRFFPVTFIGSIVWIAAFSYLM 740
            |:|..|..:  |:.|...:.:.:..|:.:.::.|:|:....|.:..|.::|..|.||||||||::
Zfish   407 ENEISPFRL--PEGAMDTVKFFISWPISLLLYFTIPNCAKKRWECCFMLSFFLSTVWIAAFSYIL 469

  Fly   741 VWWANVAGDTARIPPEVMGLTFLAAGTSIPDLITSVIVARKGFGDMAVSSSVGSNIFDVTVGLPI 805
            ||...:.|.|..||..:||:||||||||:||.|.|:||||:|.||||||:::|||:||:.|||.:
Zfish   470 VWMVTIVGYTLGIPDVIMGITFLAAGTSVPDCIASLIVARQGLGDMAVSNTIGSNVFDILVGLGV 534

  Fly   806 PWLL--YGIIYGAPVEVNSVGMVCSITILFMMLVFVVMSIACFRWRMNKGLGFTMFLLYFAFVAV 868
            ||.:  ..:.||:.|::||.|:|.|:.:|...:...|:.|...|||::..||..:.:||..|:..
Zfish   535 PWGIQTMAVNYGSVVKINSRGLVYSVVLLLGSVALTVLGIHVNRWRLDLRLGIYVLVLYAIFLTF 599

  Fly   869 SLMFEYDVIT 878
            |:|.||:|.|
Zfish   600 SIMIEYNVFT 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nckx30C	NP_652011.3	Na_Ca_ex	336..480	CDD:279963	85/143 (59%)
		Na_Ca_ex	721..871	CDD:279963	72/151 (48%)
slc24a4a	XP_005158898.1	TIGR00367	119..596	CDD:273039	196/546 (36%)
		Na_Ca_ex	120..262	CDD:279963	84/141 (60%)
		Na_Ca_ex	451..602	CDD:279963	72/150 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1168500at2759
OrthoFinder	1	1.000	-	-		FOG0000196
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.820