Protein Alignment Nckx30C and Slc24a5

DIOPT Version :9

• Sequence 1: NP_652011.3
• Gene: Nckx30C / 45248
• FlyBaseID: FBgn0028704
• Length: 881
• Species: Drosophila melanogaster
• Sequence 2: NP_778199.2
• Gene: Slc24a5 / 317750
• MGIID: 2677271
• Length: 501
• Species: Mus musculus
• Alignment Length: 562
• Identity: 173/562 - (30%)
• Similarity: 276/562 - (49%)
• Gaps: 126/562 - (22%)

  Fly   318 FPKDLFTKEQLENGAVILHIIGVIYMFVALAIVCDEFFVPSLDVIIEKLGITDDVAGATFMAAGG 382
            ||:..|||::..:|.::::.:.::||.:|::||||::|:|||::|.:.||::.|||||||||||.
Mouse    54 FPEGFFTKQESTDGGIVIYFLIILYMCMAISIVCDKYFLPSLEIISDSLGLSQDVAGATFMAAGS 118

  Fly   383 SAPELFTSVIGVFVSFDDVGIGTIVGSAVFNILFVIGMCALFSKTVLSLTWWPLFRDCSFYSISL 447
            |||||.|:.:|||::..|:||.||:|||::|:|.:...|.|.|..|.:|:.|||||||:.|::|:
Mouse   119 SAPELVTAFLGVFITKGDIGISTILGSAIYNLLGICAACGLLSNMVSTLSCWPLFRDCAVYAVSV 183

  Fly   448 LVLIYFFRDNRIFWWEALILFTIYIGYVAFMKWNVQVETCVKKMITKNKVTRVRSTDQLMPAGNA 512
            ..:.....||||:|:|...|..||..||..:.::..:...|.|..:.......|:.::.:
Mouse   184 GAVFGIIFDNRIYWYEGAGLLLIYGLYVLLLCFDTTISRHVMKTCSPCCPCLARAMEERI----- 243

  Fly   513 ANSSETSMATQPGGSVTSRAASETRSGPPGSSNAGATGNSSGGGGTSGSTQTGAKFRHGLLQLMI 577
              ..:|.:..:....:..|..|.|.|                                |:.|
Mouse   244 --EQQTLLGWEDESQLFIRRQSRTDS--------------------------------GIFQ--- 271

  Fly   578 HTIDPLHDGKVDEKATQLHAIASLKVLLDATKPQRGGATTSAANHVKINLKETTLADRPNGNIDT 642
                  .|....:.:..||.::.:.
Mouse   272 ------EDSGYSQLSLSLHGLSQVS---------------------------------------- 290

  Fly   643 TLDSPSLSGRRPSWIEQRVKIQTRKFSIKAPEIEDEPEPLSMAWPDTARKRLTYVLVAPLLVPMW 707
                                             ||.|...||  |:...:|:.:||..|::..:.
Mouse   291 ---------------------------------EDPPSVFSM--PEADLRRIFWVLSLPIITLLA 320

  Fly   708 LTLPDTRTPRGKRFFPVTFIGSIVWIAAFSYLMVWWANVAGDTARIPPEVMGLTFLAAGTSIPDL 772
            ||.||.|....|.:|.:||..|.:||:||:|::||...|.|:|..||..|||||.|||||||||.
Mouse   321 LTTPDCRRKFWKNYFVITFFMSALWISAFTYILVWMVTVTGETLGIPDTVMGLTLLAAGTSIPDT 385

  Fly   773 ITSVIVARKGFGDMAVSSSVGSNIFDVTVGLPIPWLLYGII--YGAPVEVNSVGMVCSITILFMM 835
            :|||:|||||.||||:|:.||||:||: :.|.:||.:....  ..||:||||.|:......|.:.
Mouse   386 VTSVLVARKGKGDMAISNIVGSNVFDM-LCLGLPWFIKTAFTNASAPIEVNSKGLTYITISLNIS 449

  Fly   836 LVFVVMSIACFRWRMNKGLGFTMFLLYFAFVAVSLMFEYDVI 877
            ::|:.:::....|::::.||....:||.....:|:::|..:|
Mouse   450 ILFLFLAVHFNGWKLDRKLGVVCLVLYLGLATLSVLYEIGII 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nckx30C	NP_652011.3	Na_Ca_ex	336..480	CDD:279963	69/143 (48%)
		Na_Ca_ex	721..871	CDD:279963	67/151 (44%)
Slc24a5	NP_778199.2	Na_Ca_ex	72..216	CDD:279963	69/143 (48%)
		TIGR00367	77..477	CDD:273039	163/523 (31%)
		Na_Ca_ex	334..485	CDD:279963	67/151 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1168500at2759
OrthoFinder	1	1.000	-	-		FOG0000196
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820